Isolation and Structure of Peptaibolin, a New Peptaibol from Sepedonium Strains

Isolation and Structure of Peptaibolin, a New Peptaibol from Sepedonium Strains

In the course of a screening aimed at new metabolities, we used electrospray mass spectrometry (ESI-MS, CID-MS/MS) for the detection of linear peptides and peptaibols in microbial culture extracts. Here we report the isolation and structure elucidation of peptaibolin as an unusual representative of...

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Veröffentlicht in:Journal of antibiotics 1998/11/25, Vol.51(11), pp.1055-1058
Hauptverfasser: HÜLSMANN, HEIKE, HEINZE, STEPHAN, RITZAU, MICHAEL, SCHLEGEL, BRIGITTE, GRÄFE, UDO
Format: Artikel
Sprache:eng
Schlagworte:
Anti-Bacterial Agents - chemistry
Anti-Bacterial Agents - isolation & purification
Molecular Structure
Peptaibols
Peptides - chemistry
Peptides - isolation & purification
Sepedonium
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Zusammenfassung:In the course of a screening aimed at new metabolities, we used electrospray mass spectrometry (ESI-MS, CID-MS/MS) for the detection of linear peptides and peptaibols in microbial culture extracts. Here we report the isolation and structure elucidation of peptaibolin as an unusual representative of the peptaibol family of lipophilic antibiotics.
ISSN:0021-8820
1881-1469
DOI:10.7164/antibiotics.51.1055