Antioxidant Vitamins and Coronary Artery Disease Risk in South African Males

Decreased antioxidant–vitamin nutritional status may increase lipid peroxidation and susceptibility of low-density lipoprotein (LDL) to oxidative modification. The aim of this study was to evaluate the vitamin nutritional status of coronary artery disease (CAD) patients and to assess the risk of CAD...

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Veröffentlicht in:	Clinica chimica acta 1998-11, Vol.278 (1), p.55-60
Hauptverfasser:	Delport, Rhena, B Ubbink, Johan, A. Human, Johanna, J Becker, Piet, P Myburgh, Dirk, Hayward Vermaak, WJ
Format:	Artikel
Sprache:	eng
Schlagworte:	Adult Antioxidants - therapeutic use Biological and medical sciences CAD risk Cardiology. Vascular system Cholesterol, HDL - blood Cholesterol, LDL - blood Coronary Disease - epidemiology Coronary Disease - metabolism Coronary Disease - prevention & control Coronary heart disease Heart Humans Lipid Peroxidation Male Medical sciences Middle Aged Smoking South Africa - epidemiology Vitamin A Vitamin C Vitamin E Vitamins - therapeutic use
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Zusammenfassung:	Decreased antioxidant–vitamin nutritional status may increase lipid peroxidation and susceptibility of low-density lipoprotein (LDL) to oxidative modification. The aim of this study was to evaluate the vitamin nutritional status of coronary artery disease (CAD) patients and to assess the risk of CAD related to each individual antioxidant vitamin. The study was performed as a case-control study with 41 patients with angiographically demonstrated CAD and 41 apparently healthy age- and smoking status-matched controls. Plasma vitamin E, C and A concentrations were significantly decreased in CAD patients compared with controls (p
ISSN:	0009-8981 1873-3492
DOI:	10.1016/S0009-8981(98)00131-4