Soluble P-selectin and vascular endothelial growth factor in steady state sickle cell disease: relationship to genotype

Sickle cell disease (SCD) is characterised by abnormal coagulopathy and angiogenesis although their relationships in two common genotypes, homozygous (HbSS) SCD and sickle-haemoglobin C disease (HbSC), are unexplored. We measured markers of platelet activation (soluble P-selectin [sP-selectin]), fib...

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Veröffentlicht in:	Journal of thrombosis and thrombolysis 2008-04, Vol.25 (2), p.185-189
Hauptverfasser:	Blann, A. D., Mohan, J. S., Bareford, D., Lip, G. Y. H.
Format:	Artikel
Sprache:	eng
Schlagworte:	Blood Coagulation - physiology Cardiology Case-Control Studies Cross-Sectional Studies Female Fibrin Fibrinogen Degradation Products - metabolism Genotype Hematology Hemoglobin SC Disease - blood Hemoglobin SC Disease - genetics Hemoglobin, Sickle - genetics Humans Male Medicine Medicine & Public Health Neovascularization, Physiologic - physiology P-Selectin - blood Platelet Activation - physiology Platelet Count Vascular Endothelial Growth Factor A - blood
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