Mannan binding lectin and the sudden infant death syndrome
Mannan binding lectin (MBL) may be important for innate immunity and some cases of sudden infant death syndrome (SIDS) may be preceded by bacterial infection. Therefore, relative MBL deficiency might be associated with susceptibility to SIDS. We measured MBL concentrations in 46 SIDS infants and 26...
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| Veröffentlicht in: | Forensic science international 1998-11, Vol.97 (2), p.135-138 |
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| creator | Kilpatrick, D.C James, V.S Blackwell, C.C Weir, D.M Hallam, N.F Busuttil, A |
| description | Mannan binding lectin (MBL) may be important for innate immunity and some cases of sudden infant death syndrome (SIDS) may be preceded by bacterial infection. Therefore, relative MBL deficiency might be associated with susceptibility to SIDS. We measured MBL concentrations in 46 SIDS infants and 26 controls. The proportion of subjects with low MBL values was similar in the two groups. However, the mean for the SIDS group (3 μg/ml) was higher than that of the controls (2.2 μg/ml;
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| doi_str_mv | 10.1016/S0379-0738(98)00149-2 |
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P<0.05). We interpret this difference as due to acute phase responses and suggest these findings are consistent with the view that some cot deaths are preceded by bacterial infections.</description><identifier>ISSN: 0379-0738</identifier><identifier>EISSN: 1872-6283</identifier><identifier>DOI: 10.1016/S0379-0738(98)00149-2</identifier><identifier>PMID: 9871992</identifier><identifier>CODEN: FSINDR</identifier><language>eng</language><publisher>Kidlington: Elsevier Ireland Ltd</publisher><subject>Anesthesia. Intensive care medicine. Transfusions. Cell therapy and gene therapy ; Autopsies ; Babies ; Bacterial diseases ; Bacterial infections ; Bacterial Infections - complications ; Binding ; Biological and medical sciences ; Biomarkers - blood ; Carrier Proteins - blood ; Collectins ; Cot deaths ; Emergency and intensive care: neonates and children. Prematurity. Sudden death ; Enzyme-Linked Immunosorbent Assay ; Female ; Humans ; Infant ; Infants ; Infections ; Innate immunity ; Intensive care medicine ; Lectins ; Lectins - blood ; Male ; Mannan ; Mannan binding lectin ; Mannans - blood ; Mannose-binding lectin ; Medical sciences ; Sensitivity and Specificity ; SIDS ; Sudden Infant Death - blood ; Sudden Infant Death - diagnosis ; Sudden Infant Death - etiology ; Sudden infant death syndrome ; Viral infections</subject><ispartof>Forensic science international, 1998-11, Vol.97 (2), p.135-138</ispartof><rights>1998 Elsevier Science Ireland Ltd</rights><rights>1999 INIST-CNRS</rights><rights>1998. Elsevier Science Ireland Ltd</rights><lds50>peer_reviewed</lds50><woscitedreferencessubscribed>false</woscitedreferencessubscribed><citedby>FETCH-LOGICAL-c448t-64eaea0ae4c64b529d2120016b34e0fa386996cd57efa8f7985ec5c6767a384b3</citedby><cites>FETCH-LOGICAL-c448t-64eaea0ae4c64b529d2120016b34e0fa386996cd57efa8f7985ec5c6767a384b3</cites></display><links><openurl>$$Topenurl_article</openurl><openurlfulltext>$$Topenurlfull_article</openurlfulltext><thumbnail>$$Tsyndetics_thumb_exl</thumbnail><linktohtml>$$Uhttps://www.proquest.com/docview/2900101128?pq-origsite=primo$$EHTML$$P50$$Gproquest$$H</linktohtml><link.rule.ids>314,780,784,3550,27924,27925,45995,64385,64387,64389,72341</link.rule.ids><backlink>$$Uhttp://pascal-francis.inist.fr/vibad/index.php?action=getRecordDetail&idt=1630337$$DView record in Pascal Francis$$Hfree_for_read</backlink><backlink>$$Uhttps://www.ncbi.nlm.nih.gov/pubmed/9871992$$D View this record in MEDLINE/PubMed$$Hfree_for_read</backlink></links><search><creatorcontrib>Kilpatrick, D.C</creatorcontrib><creatorcontrib>James, V.S</creatorcontrib><creatorcontrib>Blackwell, C.C</creatorcontrib><creatorcontrib>Weir, D.M</creatorcontrib><creatorcontrib>Hallam, N.F</creatorcontrib><creatorcontrib>Busuttil, A</creatorcontrib><title>Mannan binding lectin and the sudden infant death syndrome</title><title>Forensic science international</title><addtitle>Forensic Sci Int</addtitle><description>Mannan binding lectin (MBL) may be important for innate immunity and some cases of sudden infant death syndrome (SIDS) may be preceded by bacterial infection. Therefore, relative MBL deficiency might be associated with susceptibility to SIDS. We measured MBL concentrations in 46 SIDS infants and 26 controls. The proportion of subjects with low MBL values was similar in the two groups. However, the mean for the SIDS group (3 μg/ml) was higher than that of the controls (2.2 μg/ml;
P<0.05). We interpret this difference as due to acute phase responses and suggest these findings are consistent with the view that some cot deaths are preceded by bacterial infections.</description><subject>Anesthesia. Intensive care medicine. Transfusions. Cell therapy and gene therapy</subject><subject>Autopsies</subject><subject>Babies</subject><subject>Bacterial diseases</subject><subject>Bacterial infections</subject><subject>Bacterial Infections - complications</subject><subject>Binding</subject><subject>Biological and medical sciences</subject><subject>Biomarkers - blood</subject><subject>Carrier Proteins - blood</subject><subject>Collectins</subject><subject>Cot deaths</subject><subject>Emergency and intensive care: neonates and children. Prematurity. Sudden death</subject><subject>Enzyme-Linked Immunosorbent Assay</subject><subject>Female</subject><subject>Humans</subject><subject>Infant</subject><subject>Infants</subject><subject>Infections</subject><subject>Innate immunity</subject><subject>Intensive care medicine</subject><subject>Lectins</subject><subject>Lectins - blood</subject><subject>Male</subject><subject>Mannan</subject><subject>Mannan binding lectin</subject><subject>Mannans - blood</subject><subject>Mannose-binding lectin</subject><subject>Medical sciences</subject><subject>Sensitivity and Specificity</subject><subject>SIDS</subject><subject>Sudden Infant Death - blood</subject><subject>Sudden Infant Death - diagnosis</subject><subject>Sudden Infant Death - etiology</subject><subject>Sudden infant death syndrome</subject><subject>Viral infections</subject><issn>0379-0738</issn><issn>1872-6283</issn><fulltext>true</fulltext><rsrctype>article</rsrctype><creationdate>1998</creationdate><recordtype>article</recordtype><sourceid>EIF</sourceid><sourceid>8G5</sourceid><sourceid>ABUWG</sourceid><sourceid>AFKRA</sourceid><sourceid>AZQEC</sourceid><sourceid>BENPR</sourceid><sourceid>CCPQU</sourceid><sourceid>DWQXO</sourceid><sourceid>GNUQQ</sourceid><sourceid>GUQSH</sourceid><sourceid>M2O</sourceid><recordid>eNqFkUtLHEEUhQuJTCZjfsJAg0GSRWs9ul5uJEiiguIiybqorrrt1NBTrVXdAf99apzBgBtXd3G-e7j3HISWBJ8STMTZL8ykrrFk6qtW3zAmja7pAZoTJWktqGIf0PwV-Yg-5bzGGHNOxQzNtJJEazpH53c2RhurNkQf4kPVgxtDrGz01biCKk_eQ6xC7GwcKw92XFX5Ofo0bOAIHXa2z_B5Pxfoz88fvy-v69v7q5vL77e1axo11qIBCxZbaJxoWk61p4SWc0XLGsCdZUpoLZznEjqrOqkVB8edkEIWrWnZAp3sfB_T8DRBHs0mZAd9byMMUzZCE8K0kO-CRHKpGOcFPH4DrocpxfKEobqchgkp-S0Q31EuDTkn6MxjChubng3BZluBeanAbPM1WpmXCgwte8u9-9RuwL9u7TMv-pe9brOzfZdsdCH_NxcMM7b95mKHQcn2b4BksgsQHfiQSknGD-GdQ_4BGdWgYQ</recordid><startdate>19981109</startdate><enddate>19981109</enddate><creator>Kilpatrick, D.C</creator><creator>James, V.S</creator><creator>Blackwell, C.C</creator><creator>Weir, D.M</creator><creator>Hallam, N.F</creator><creator>Busuttil, A</creator><general>Elsevier Ireland Ltd</general><general>Elsevier</general><general>Elsevier Limited</general><scope>IQODW</scope><scope>CGR</scope><scope>CUY</scope><scope>CVF</scope><scope>ECM</scope><scope>EIF</scope><scope>NPM</scope><scope>AAYXX</scope><scope>CITATION</scope><scope>3V.</scope><scope>7QP</scope><scope>7RV</scope><scope>7U7</scope><scope>7X7</scope><scope>7XB</scope><scope>88E</scope><scope>8FE</scope><scope>8FH</scope><scope>8FI</scope><scope>8FJ</scope><scope>8FK</scope><scope>8G5</scope><scope>ABUWG</scope><scope>AFKRA</scope><scope>AZQEC</scope><scope>BBNVY</scope><scope>BENPR</scope><scope>BHPHI</scope><scope>C1K</scope><scope>CCPQU</scope><scope>DWQXO</scope><scope>FYUFA</scope><scope>GHDGH</scope><scope>GNUQQ</scope><scope>GUQSH</scope><scope>HCIFZ</scope><scope>K9.</scope><scope>KB0</scope><scope>LK8</scope><scope>M0S</scope><scope>M1P</scope><scope>M2O</scope><scope>M7P</scope><scope>MBDVC</scope><scope>NAPCQ</scope><scope>PQEST</scope><scope>PQQKQ</scope><scope>PQUKI</scope><scope>Q9U</scope><scope>7QL</scope><scope>7X8</scope></search><sort><creationdate>19981109</creationdate><title>Mannan binding lectin and the sudden infant death syndrome</title><author>Kilpatrick, D.C ; James, V.S ; Blackwell, C.C ; Weir, D.M ; Hallam, N.F ; Busuttil, A</author></sort><facets><frbrtype>5</frbrtype><frbrgroupid>cdi_FETCH-LOGICAL-c448t-64eaea0ae4c64b529d2120016b34e0fa386996cd57efa8f7985ec5c6767a384b3</frbrgroupid><rsrctype>articles</rsrctype><prefilter>articles</prefilter><language>eng</language><creationdate>1998</creationdate><topic>Anesthesia. Intensive care medicine. Transfusions. Cell therapy and gene therapy</topic><topic>Autopsies</topic><topic>Babies</topic><topic>Bacterial diseases</topic><topic>Bacterial infections</topic><topic>Bacterial Infections - complications</topic><topic>Binding</topic><topic>Biological and medical sciences</topic><topic>Biomarkers - blood</topic><topic>Carrier Proteins - blood</topic><topic>Collectins</topic><topic>Cot deaths</topic><topic>Emergency and intensive care: neonates and children. Prematurity. Sudden death</topic><topic>Enzyme-Linked Immunosorbent Assay</topic><topic>Female</topic><topic>Humans</topic><topic>Infant</topic><topic>Infants</topic><topic>Infections</topic><topic>Innate immunity</topic><topic>Intensive care medicine</topic><topic>Lectins</topic><topic>Lectins - blood</topic><topic>Male</topic><topic>Mannan</topic><topic>Mannan binding lectin</topic><topic>Mannans - blood</topic><topic>Mannose-binding lectin</topic><topic>Medical sciences</topic><topic>Sensitivity and Specificity</topic><topic>SIDS</topic><topic>Sudden Infant Death - blood</topic><topic>Sudden Infant Death - diagnosis</topic><topic>Sudden Infant Death - etiology</topic><topic>Sudden infant death syndrome</topic><topic>Viral infections</topic><toplevel>peer_reviewed</toplevel><toplevel>online_resources</toplevel><creatorcontrib>Kilpatrick, D.C</creatorcontrib><creatorcontrib>James, V.S</creatorcontrib><creatorcontrib>Blackwell, C.C</creatorcontrib><creatorcontrib>Weir, D.M</creatorcontrib><creatorcontrib>Hallam, N.F</creatorcontrib><creatorcontrib>Busuttil, A</creatorcontrib><collection>Pascal-Francis</collection><collection>Medline</collection><collection>MEDLINE</collection><collection>MEDLINE (Ovid)</collection><collection>MEDLINE</collection><collection>MEDLINE</collection><collection>PubMed</collection><collection>CrossRef</collection><collection>ProQuest Central (Corporate)</collection><collection>Calcium & Calcified Tissue Abstracts</collection><collection>ProQuest Nursing and Allied Health Journals</collection><collection>Toxicology Abstracts</collection><collection>ProQuest Health and Medical</collection><collection>ProQuest Central (purchase pre-March 2016)</collection><collection>Medical Database (Alumni Edition)</collection><collection>ProQuest SciTech Collection</collection><collection>ProQuest Natural Science Collection</collection><collection>Hospital Premium Collection</collection><collection>Hospital Premium Collection (Alumni Edition)</collection><collection>ProQuest Central (Alumni) (purchase pre-March 2016)</collection><collection>Research Library (Alumni Edition)</collection><collection>ProQuest Central (Alumni Edition)</collection><collection>ProQuest Central UK/Ireland</collection><collection>ProQuest Central Essentials</collection><collection>Biological Science Collection</collection><collection>ProQuest Central</collection><collection>Natural Science Collection</collection><collection>Environmental Sciences and Pollution Management</collection><collection>ProQuest One Community College</collection><collection>ProQuest Central Korea</collection><collection>Health Research Premium Collection</collection><collection>Health Research Premium Collection (Alumni)</collection><collection>ProQuest Central Student</collection><collection>Research Library Prep</collection><collection>SciTech Premium Collection</collection><collection>ProQuest Health & Medical Complete (Alumni)</collection><collection>Nursing & Allied Health Database (Alumni Edition)</collection><collection>ProQuest Biological Science Collection</collection><collection>Health & Medical Collection (Alumni Edition)</collection><collection>Medical Database</collection><collection>ProQuest Research Library</collection><collection>ProQuest Biological Science Journals</collection><collection>Research Library (Corporate)</collection><collection>Nursing & Allied Health Premium</collection><collection>ProQuest One Academic Eastern Edition (DO NOT USE)</collection><collection>ProQuest One Academic</collection><collection>ProQuest One Academic UKI Edition</collection><collection>ProQuest Central Basic</collection><collection>Bacteriology Abstracts (Microbiology B)</collection><collection>MEDLINE - Academic</collection><jtitle>Forensic science international</jtitle></facets><delivery><delcategory>Remote Search Resource</delcategory><fulltext>fulltext</fulltext></delivery><addata><au>Kilpatrick, D.C</au><au>James, V.S</au><au>Blackwell, C.C</au><au>Weir, D.M</au><au>Hallam, N.F</au><au>Busuttil, A</au><format>journal</format><genre>article</genre><ristype>JOUR</ristype><atitle>Mannan binding lectin and the sudden infant death syndrome</atitle><jtitle>Forensic science international</jtitle><addtitle>Forensic Sci Int</addtitle><date>1998-11-09</date><risdate>1998</risdate><volume>97</volume><issue>2</issue><spage>135</spage><epage>138</epage><pages>135-138</pages><issn>0379-0738</issn><eissn>1872-6283</eissn><coden>FSINDR</coden><abstract>Mannan binding lectin (MBL) may be important for innate immunity and some cases of sudden infant death syndrome (SIDS) may be preceded by bacterial infection. Therefore, relative MBL deficiency might be associated with susceptibility to SIDS. We measured MBL concentrations in 46 SIDS infants and 26 controls. The proportion of subjects with low MBL values was similar in the two groups. However, the mean for the SIDS group (3 μg/ml) was higher than that of the controls (2.2 μg/ml;
P<0.05). We interpret this difference as due to acute phase responses and suggest these findings are consistent with the view that some cot deaths are preceded by bacterial infections.</abstract><cop>Kidlington</cop><pub>Elsevier Ireland Ltd</pub><pmid>9871992</pmid><doi>10.1016/S0379-0738(98)00149-2</doi><tpages>4</tpages></addata></record> |
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| ispartof | Forensic science international, 1998-11, Vol.97 (2), p.135-138 |
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| source | MEDLINE; ScienceDirect Journals (5 years ago - present); ProQuest Central UK/Ireland |
| subjects | Anesthesia. Intensive care medicine. Transfusions. Cell therapy and gene therapy Autopsies Babies Bacterial diseases Bacterial infections Bacterial Infections - complications Binding Biological and medical sciences Biomarkers - blood Carrier Proteins - blood Collectins Cot deaths Emergency and intensive care: neonates and children. Prematurity. Sudden death Enzyme-Linked Immunosorbent Assay Female Humans Infant Infants Infections Innate immunity Intensive care medicine Lectins Lectins - blood Male Mannan Mannan binding lectin Mannans - blood Mannose-binding lectin Medical sciences Sensitivity and Specificity SIDS Sudden Infant Death - blood Sudden Infant Death - diagnosis Sudden Infant Death - etiology Sudden infant death syndrome Viral infections |
| title | Mannan binding lectin and the sudden infant death syndrome |
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