Mannan binding lectin and the sudden infant death syndrome

Mannan binding lectin and the sudden infant death syndrome

Mannan binding lectin (MBL) may be important for innate immunity and some cases of sudden infant death syndrome (SIDS) may be preceded by bacterial infection. Therefore, relative MBL deficiency might be associated with susceptibility to SIDS. We measured MBL concentrations in 46 SIDS infants and 26...

Ausführliche Beschreibung

Gespeichert in:
Bibliographische Detailangaben
Veröffentlicht in:Forensic science international 1998-11, Vol.97 (2), p.135-138
Hauptverfasser: Kilpatrick, D.C, James, V.S, Blackwell, C.C, Weir, D.M, Hallam, N.F, Busuttil, A
Format: Artikel
Sprache:eng
Schlagworte:
Anesthesia. Intensive care medicine. Transfusions. Cell therapy and gene therapy
Autopsies
Babies
Bacterial diseases
Bacterial infections
Bacterial Infections - complications
Binding
Biological and medical sciences
Biomarkers - blood
Carrier Proteins - blood
Collectins
Cot deaths
Emergency and intensive care: neonates and children. Prematurity. Sudden death
Enzyme-Linked Immunosorbent Assay
Female
Humans
Infant
Infants
Infections
Innate immunity
Intensive care medicine
Lectins
Lectins - blood
Male
Mannan
Mannan binding lectin
Mannans - blood
Mannose-binding lectin
Medical sciences
Sensitivity and Specificity
SIDS
Sudden Infant Death - blood
Sudden Infant Death - diagnosis
Sudden Infant Death - etiology
Sudden infant death syndrome
Viral infections
Online-Zugang:Volltext
Tags: Tag hinzufügen
Keine Tags, Fügen Sie den ersten Tag hinzu!
Beschreibung
Zusammenfassung:Mannan binding lectin (MBL) may be important for innate immunity and some cases of sudden infant death syndrome (SIDS) may be preceded by bacterial infection. Therefore, relative MBL deficiency might be associated with susceptibility to SIDS. We measured MBL concentrations in 46 SIDS infants and 26 controls. The proportion of subjects with low MBL values was similar in the two groups. However, the mean for the SIDS group (3 μg/ml) was higher than that of the controls (2.2 μg/ml; P
ISSN:0379-0738
1872-6283
DOI:10.1016/S0379-0738(98)00149-2