Reversible Bone Marrow Dysplasia in Patients with Systemic Lupus Erythematosus

Objective Several reports of bone marrow dysplasia in patients with systemic lupus erythematosus (SLE) have been published. However, the reports are restricted primarily to descriptions of the erythroid lineage; no follow-up studies have been reported, and the clinical significance of the dysplasias...

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Veröffentlicht in:	Internal Medicine 2008, Vol.47(8), pp.737-742
Hauptverfasser:	Oka, Yumiko, Kameoka, Junichi, Hirabayashi, Yasuhiko, Takahashi, Reiko, Ishii, Tomonori, Sasaki, Takeshi, Harigae, Hideo
Format:	Artikel
Sprache:	eng
Schlagworte:	Adolescent Adult Biopsy, Fine-Needle Bone Diseases, Developmental - etiology Bone Diseases, Developmental - pathology bone marrow Bone Marrow - pathology Child cytopenia dysplasia Female Humans Lupus Erythematosus, Systemic - complications Lupus Erythematosus, Systemic - pathology Male Megakaryocytes - pathology Megaloblasts - pathology Middle Aged myelodysplastic syndrome Myeloid Cells - pathology Remission, Spontaneous Retrospective Studies Severity of Illness Index systemic lupus erythematosus
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Zusammenfassung:	Objective Several reports of bone marrow dysplasia in patients with systemic lupus erythematosus (SLE) have been published. However, the reports are restricted primarily to descriptions of the erythroid lineage; no follow-up studies have been reported, and the clinical significance of the dysplasias is unknown. Therefore, in the present study, the dysplasias noted in bone marrow aspirates obtained from SLE patients were characterized. Patients and Methods The smears of bone marrow aspirates obtained from 17 SLE patients who had bone marrow aspiration due to cytopenia (WBC
ISSN:	0918-2918 1349-7235
DOI:	10.2169/internalmedicine.47.0607