AZT Trials and Tribulations

Crouch and Arras consider whether placebo-controlled trials are justified in LDCs when a proven treatment already exists in developed countries, focusing on trials involving AZT to prevent maternal-infant HIV transmission.

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Bibliographische Detailangaben
Veröffentlicht in:	The Hastings Center report 1998-11, Vol.28 (6), p.26-34
Hauptverfasser:	Crouch, Robert A., Arras, John D.
Format:	Artikel
Sprache:	eng
Schlagworte:	AIDS AIDS/HIV Anti-HIV Agents - therapeutic use Bioethics Centers for Disease Control and Prevention (U.S.) Clinical trials Clinical Trials as Topic Control Groups Developed countries Developing Countries Disease transmission Drug therapy Ethics, Medical Experimentation Female Health aspects HIV HIV infection HIV infections HIV Infections - drug therapy HIV Infections - transmission Host country Human immunodeficiency virus Humans Industrialized nations Infectious Disease Transmission, Vertical - prevention & control Internationality LDCs Maternal-fetal exchange Medical ethics Moral Obligations Patient Advocacy Placebos Pregnancy Pregnancy Complications, Infectious - drug therapy Pregnant Women Research ethics Research Subjects Resource Allocation Symposium: A World of Research Subjects Testing Thailand Therapeutic Human Experimentation United States Zidovudine Zidovudine - therapeutic use
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Beschreibung
Zusammenfassung:	Crouch and Arras consider whether placebo-controlled trials are justified in LDCs when a proven treatment already exists in developed countries, focusing on trials involving AZT to prevent maternal-infant HIV transmission.
ISSN:	0093-0334 1552-146X
DOI:	10.2307/3528266