Importance of endothelial function in mediating the benefits of lipid-lowering therapy

Trials of lipid lowering by various methods have clearly demonstrated the benefits, clinically and angiographically. Evidence of slowed arterial disease progression and even regression has been convincing but modest, at best. For example, among those treated intensively in the Familial Atheroscleros...

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Veröffentlicht in:	The American journal of cardiology 1998-11, Vol.82 (10), p.49-52
Hauptverfasser:	Brown, B.Greg, Zhao, Xue-Qiao
Format:	Artikel
Sprache:	eng
Schlagworte:	Biological and medical sciences Cardiovascular disease Coronary Artery Disease - drug therapy Coronary Artery Disease - etiology Coronary Artery Disease - pathology Endothelium, Vascular - physiology General and cellular metabolism. Vitamins Humans Hyperlipidemias - complications Hypolipidemic Agents - therapeutic use Lipids Medical sciences Pharmacology. Drug treatments Therapy
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Beschreibung
Zusammenfassung:	Trials of lipid lowering by various methods have clearly demonstrated the benefits, clinically and angiographically. Evidence of slowed arterial disease progression and even regression has been convincing but modest, at best. For example, among those treated intensively in the Familial Atherosclerosis Treatment Study (FATS), the mean improvement in proximal stenosis severity was
ISSN:	0002-9149 1879-1913
DOI:	10.1016/S0002-9149(98)00726-7