A placebo-controlled study of growth hormone in patients with congestive heart failure

A placebo-controlled study of growth hormone in patients with congestive heart failure

Aim Experimental data in heart failure models and an open trial of seven patients with idiopathic dilated cardiomyo-pathy have suggested beneficial effects of growth hormone on cardiac function. The aim of the present study was to evaluate growth hormone effects on cardiac function in a placebo-cont...

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Veröffentlicht in:European heart journal 1998-11, Vol.19 (11), p.1704-1711
Hauptverfasser: Isgaard, J., Bergh, C.-H., Caidahl, K., Lomsky, M., Hjalmarson, Å., Bengtsson, B.-Å.
Format: Artikel
Sprache:eng
Schlagworte:
Angiotensin-Converting Enzyme Inhibitors - therapeutic use
Biological and medical sciences
Congestive heart failure
Doppler echocardiography
Double-Blind Method
Echocardiography, Doppler
Female
growth hormone
Growth Hormone - therapeutic use
Heart Failure - diagnostic imaging
Heart Failure - drug therapy
Heart Failure - etiology
Heart Failure - physiopathology
Hormones. Endocrine system
Humans
Insulin-Like Growth Factor I - therapeutic use
insulin-like growth factor-I
Male
Medical sciences
Middle Aged
Pharmacology. Drug treatments
Radionuclide Angiography
Treatment Outcome
Ventricular Function, Left
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Zusammenfassung:Aim Experimental data in heart failure models and an open trial of seven patients with idiopathic dilated cardiomyo-pathy have suggested beneficial effects of growth hormone on cardiac function. The aim of the present study was to evaluate growth hormone effects on cardiac function in a placebo-controlled study. Methods Twenty two patients with congestive heart failure of different aetiologies in NYHA II and III and an echocardiographic ejection fraction
ISSN:0195-668X
1522-9645
DOI:10.1053/euhj.1998.1123