Calcium Signaling
Calcium ions (Ca 2+) impact nearly every aspect of cellular life. This review examines the principles of Ca 2+ signaling, from changes in protein conformations driven by Ca 2+ to the mechanisms that control Ca 2+ levels in the cytoplasm and organelles. Also discussed is the highly localized nature o...
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| Veröffentlicht in: | Cell 2007-12, Vol.131 (6), p.1047-1058 |
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| container_issue | 6 |
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| container_title | Cell |
| container_volume | 131 |
| creator | Clapham, David E. |
| description | Calcium ions (Ca
2+) impact nearly every aspect of cellular life. This review examines the principles of Ca
2+ signaling, from changes in protein conformations driven by Ca
2+ to the mechanisms that control Ca
2+ levels in the cytoplasm and organelles. Also discussed is the highly localized nature of Ca
2+-mediated signal transduction and its specific roles in excitability, exocytosis, motility, apoptosis, and transcription. |
| doi_str_mv | 10.1016/j.cell.2007.11.028 |
| format | Article |
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2+) impact nearly every aspect of cellular life. This review examines the principles of Ca
2+ signaling, from changes in protein conformations driven by Ca
2+ to the mechanisms that control Ca
2+ levels in the cytoplasm and organelles. Also discussed is the highly localized nature of Ca
2+-mediated signal transduction and its specific roles in excitability, exocytosis, motility, apoptosis, and transcription.</abstract><cop>United States</cop><pub>Elsevier Inc</pub><pmid>18083096</pmid><doi>10.1016/j.cell.2007.11.028</doi><tpages>12</tpages><oa>free_for_read</oa></addata></record> |
| fulltext | fulltext |
| identifier | ISSN: 0092-8674 |
| ispartof | Cell, 2007-12, Vol.131 (6), p.1047-1058 |
| issn | 0092-8674 1097-4172 |
| language | eng |
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| source | MEDLINE; Elsevier ScienceDirect Journals Complete; Cell Press Free Archives; Elektronische Zeitschriftenbibliothek - Frei zugängliche E-Journals |
| subjects | Animals Calcium Signaling Calcium-Binding Proteins - metabolism Calcium-Transporting ATPases - metabolism Calmodulin - metabolism Cell Membrane - metabolism Cell Movement Humans Models, Molecular Signal Transduction |
| title | Calcium Signaling |
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