Antiobesity properties of two African plants (Afromomum meleguetta and Spilanthes acmella) by pancreatic lipase inhibition

Ethanol extracts of seeds of Afromomum meleguetta and flower buds of Splilanthes acmella presented pancreatic lipase inhibitory activities in a concentration related manner under in vitro conditions. The two plants were extracted with 70% ethanol by sonication, fractionated on silica gel and tested...

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Veröffentlicht in:	Phytotherapy research 2007-12, Vol.21 (12), p.1253-1255
Hauptverfasser:	Ekanem, A.P, Wang, M, Simon, J.E, Moreno, D.A
Format:	Artikel
Sprache:	eng
Schlagworte:	Afromomum meleguetta Anti-Obesity Agents - analysis Anti-Obesity Agents - pharmacology Asteraceae - chemistry Biological and medical sciences Dietary Fats - metabolism Flowers - chemistry General pharmacology Lipase - antagonists & inhibitors lipase inhibition Medical sciences Pharmacognosy. Homeopathy. Health food Pharmacology. Drug treatments Plant Extracts - pharmacology Seeds - chemistry Spilanthes acmella Zingiberaceae - chemistry
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Zusammenfassung:	Ethanol extracts of seeds of Afromomum meleguetta and flower buds of Splilanthes acmella presented pancreatic lipase inhibitory activities in a concentration related manner under in vitro conditions. The two plants were extracted with 70% ethanol by sonication, fractionated on silica gel and tested at concentrations in the range 0.75-2.0 mg/mL. Lipase inhibitory activities of 90% and 40% were observed in A. meleguetta and S. acmella, respectively. The two plants have potentials as candidates for weight reduction and obesity control. Copyright © 2007 John Wiley & Sons, Ltd.
ISSN:	0951-418X 1099-1573
DOI:	10.1002/ptr.2239