Serine proteases, their inhibitors and allergy

This paper reviews four serine protease inhibitors and three protease gene defects that are associated with allergic conditions, suggesting an important role for these genes and their products in the development of allergy. Serine protease inhibitors may have a therapeutic potential in the treatment...

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Veröffentlicht in:	Allergy (Copenhagen) 2006-12, Vol.61 (12), p.1441-1447
Hauptverfasser:	Smith, P. K., Harper, J. I.
Format:	Artikel
Sprache:	eng
Schlagworte:	Allergic diseases allergy Animals Biological and medical sciences Fundamental and applied biological sciences. Psychology Fundamental immunology Humans Hypersensitivity - enzymology Hypersensitivity - genetics Immunopathology Medical sciences proteases Serine Endopeptidases - genetics Serine Endopeptidases - physiology serine protease inhibitors Serine Proteinase Inhibitors - physiology
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Beschreibung
Zusammenfassung:	This paper reviews four serine protease inhibitors and three protease gene defects that are associated with allergic conditions, suggesting an important role for these genes and their products in the development of allergy. Serine protease inhibitors may have a therapeutic potential in the treatment of allergy.
ISSN:	0105-4538 1398-9995
DOI:	10.1111/j.1398-9995.2006.01233.x