The multidisciplinary team meeting improves staging accuracy and treatment selection for gastro-esophageal cancer

The object of this article is to assess current staging accuracies for individual modalities and to investigate the influence of the multidisciplinary team (MDT) on clinical staging accuracies and treatment selection for patients with gastro‐esophageal cancer. Patients newly diagnosed with gastric o...

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Veröffentlicht in:Diseases of the esophagus 2006-12, Vol.19 (6), p.496-503
Hauptverfasser: Davies, A. R., Deans, D. A. C., Penman, I., Plevris, J. N., Fletcher, J., Wall, L., Phillips, H., Gilmour, H., Patel, D., De Beaux, A., Paterson-Brown, S.
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Sprache:eng
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Zusammenfassung:The object of this article is to assess current staging accuracies for individual modalities and to investigate the influence of the multidisciplinary team (MDT) on clinical staging accuracies and treatment selection for patients with gastro‐esophageal cancer. Patients newly diagnosed with gastric or esophageal cancer and who were deemed suitable for surgical resection by the MDT were studied. Patients were staged with a combination of computerized tomography (CT), endoscopic ultrasound (EUS) and laparoscopic ultrasound (LUS). Additionally, the MDT determined an overall clinical stage for each patient after discussion at the MDT meeting. Treatments were selected according to this final clinical stage. Final histopathological staging (pTNM) was available for all patients and was used as the gold standard for determining staging accuracy. Suitability of treatment selection was assessed once final pTNM was available. One hundred and eighteen patients were studied. Endoscopic ultrasound was the most accurate individual staging modality for the loco‐regional assessment of esophageal tumors (T stage accuracy 78%, N stage accuracy 70%). Laparoscopic ultrasound was the most accurate modality in T staging of gastric cancers (91%). The MDT stage was more accurate than each individual staging modality for T and N staging for both gastric and esophageal cancers (accuracy range: 88–89%) and was better for the assessment of nodal disease than each individual modality (CT P 
ISSN:1120-8694
1442-2050
DOI:10.1111/j.1442-2050.2006.00629.x