Antimüllerian hormone and pituitary gland activity after prolonged down-regulation with goserelin acetate

The size of the pool of growing follicles was normal after prolonged down-regulation, as indicated by normal AMH levels 4 and 8 weeks after goserelin administration. However, there was a profound down-regulation of LH levels; therefore we suggest administration of exogenous LH to proceed to IVF or a...

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Veröffentlicht in:	Fertility and sterility 2006-11, Vol.86 (5), p.1515-1517
Hauptverfasser:	Mohamed, Kamel Abdelhakim, Davies, W.A.R., Lashen, Hany
Format:	Artikel
Sprache:	eng
Schlagworte:	Anti-Mullerian Hormone Down-Regulation - drug effects Endometriosis - drug therapy Endometriosis - metabolism Female Follicle Stimulating Hormone - blood Glycoproteins - blood Goserelin - administration & dosage Humans Luteinizing Hormone - blood Pilot Projects Pituitary Gland - drug effects Pituitary Gland - metabolism Testicular Hormones - blood
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Zusammenfassung:	The size of the pool of growing follicles was normal after prolonged down-regulation, as indicated by normal AMH levels 4 and 8 weeks after goserelin administration. However, there was a profound down-regulation of LH levels; therefore we suggest administration of exogenous LH to proceed to IVF or alternatively stimulation of endogenous LH secretion with daily administration of GnRH agonist. These need to be assessed prospectively.
ISSN:	0015-0282 1556-5653
DOI:	10.1016/j.fertnstert.2006.03.047