Conformational Control of Transmembrane Cl- Transport
Preorganization of the isophthalamide cleft in N,N‘-dibutyl-4,6-dihydroxyisophthalamide (2) by means of intramolecular hydrogen bonds results in an enhanced anion receptor that displays significant chloride transport activity into EYPC liposomes. This function is easily switchable by controlling the...
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Veröffentlicht in: | Journal of the American Chemical Society 2007-02, Vol.129 (7), p.1886-1887 |
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container_end_page | 1887 |
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container_issue | 7 |
container_start_page | 1886 |
container_title | Journal of the American Chemical Society |
container_volume | 129 |
creator | Santacroce, Paul V Davis, Jeffery T Light, Mark E Gale, Philip A Iglesias-Sánchez, José Carlos Prados, Pilar Quesada, Roberto |
description | Preorganization of the isophthalamide cleft in N,N‘-dibutyl-4,6-dihydroxyisophthalamide (2) by means of intramolecular hydrogen bonds results in an enhanced anion receptor that displays significant chloride transport activity into EYPC liposomes. This function is easily switchable by controlling the pH. |
doi_str_mv | 10.1021/ja068067v |
format | Article |
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source | MEDLINE; American Chemical Society Journals |
subjects | Amides - chemistry Amides - metabolism Chlorides - chemistry Chlorides - metabolism Crystallography, X-Ray Hydrogen Bonding Ion Transport Lipid Bilayers - chemistry Lipid Bilayers - metabolism Liposomes - chemistry Models, Molecular Molecular Conformation Organic Anion Transporters - chemistry Organic Anion Transporters - metabolism Phthalic Acids - chemistry Phthalic Acids - metabolism |
title | Conformational Control of Transmembrane Cl- Transport |
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