A Human Interleukin-12/23 Monoclonal Antibody for the Treatment of Psoriasis

Type 1 cytokines are overexpressed in psoriatic plaques. This trial evaluated a monoclonal antibody against interleukin-12 and interleukin-23 in patients with psoriasis. Response rates at 12 weeks were significantly higher in patients treated with interleukin-12/23 monoclonal antibody than in those...

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Veröffentlicht in:The New England journal of medicine 2007-02, Vol.356 (6), p.580-592
Hauptverfasser: Krueger, Gerald G, Langley, Richard G, Leonardi, Craig, Yeilding, Newman, Guzzo, Cynthia, Wang, Yuhua, Dooley, Lisa T, Lebwohl, Mark
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Sprache:eng
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