A Human Interleukin-12/23 Monoclonal Antibody for the Treatment of Psoriasis
Type 1 cytokines are overexpressed in psoriatic plaques. This trial evaluated a monoclonal antibody against interleukin-12 and interleukin-23 in patients with psoriasis. Response rates at 12 weeks were significantly higher in patients treated with interleukin-12/23 monoclonal antibody than in those...
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Veröffentlicht in: | The New England journal of medicine 2007-02, Vol.356 (6), p.580-592 |
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Sprache: | eng |
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