Plasma KL-6 predicts the development and outcome of bronchopulmonary dysplasia

Circulating KL-6 is a specific indicator of pulmonary injury affecting the alveolar epithelium and interstitium. Our preliminary study suggested the usefulness of plasma KL-6 as a marker of bronchopulmonary dysplasia (BPD). To confirm the diagnostic value of KL-6 for BPD as well as to determine the...

Ausführliche Beschreibung

Gespeichert in:

Bibliographische Detailangaben
Veröffentlicht in:	Pediatric research 2006-11, Vol.60 (5), p.613-618
Hauptverfasser:	OGIHARA, Tohru, HIRANO, Kazuya, YAMAOKA, Shigeo, YASUI, Masako, MORINOBU, Takao, KIM, Han-Suk, OGAWA, Satoru, HIROI, Mayo, OUE, Shinya, BAN, Ryoichi, HIRA, Seigo, HASEGAWA, Masashi
Format:	Artikel
Sprache:	eng
Schlagworte:	Antigens, Neoplasm - blood Biological and medical sciences Biomarkers - blood Bronchopulmonary Dysplasia - blood Bronchopulmonary Dysplasia - diagnosis Female Fetal Blood - chemistry General aspects Gestational Age Humans Infant, Newborn Infant, Premature Male Medical sciences Mucin-1 Mucins - blood Pneumology Predictive Value of Tests Pregnancy Reference Values Reproducibility of Results Respiratory system : syndromes and miscellaneous diseases ROC Curve
Online-Zugang:	Volltext
Tags:	Tag hinzufügen Keine Tags, Fügen Sie den ersten Tag hinzu!

Beschreibung
Zusammenfassung:	Circulating KL-6 is a specific indicator of pulmonary injury affecting the alveolar epithelium and interstitium. Our preliminary study suggested the usefulness of plasma KL-6 as a marker of bronchopulmonary dysplasia (BPD). To confirm the diagnostic value of KL-6 for BPD as well as to determine the reference range, we conducted a larger prospective study in 135 preterm infants
ISSN:	0031-3998 1530-0447
DOI:	10.1203/01.pdr.0000242361.47408.51