Granulosa cells as indicators of oocyte quality

Granulosa-cumulus cells are located around the oocyte and may be involved in competence acquisition and in the resumption of oocyte meiosis. We assessed Bax expression in granulosa-cumulus cells and its correlation to in vitro resumption of oocyte meiosis in women presenting PCOS (polycystic ovarian...

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Veröffentlicht in:	Journal de gynécologie, obstétrique et biologie de la reproduction obstétrique et biologie de la reproduction, 2006-09, Vol.35 (5 Pt 2), p.2S14-2S18
1. Verfasser:	Machelon, V
Format:	Artikel
Sprache:	fre
Schlagworte:	bcl-2-Associated X Protein - genetics Chemokine CXCL12 Chemokines, CXC - physiology Chorionic Gonadotropin - administration & dosage Embryo, Mammalian - physiology Embryonic Development Female Fertilization in Vitro Gene Expression Granulosa Cells - physiology Humans Meiosis Oocytes - cytology Oocytes - physiology Polycystic Ovary Syndrome
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Zusammenfassung:	Granulosa-cumulus cells are located around the oocyte and may be involved in competence acquisition and in the resumption of oocyte meiosis. We assessed Bax expression in granulosa-cumulus cells and its correlation to in vitro resumption of oocyte meiosis in women presenting PCOS (polycystic ovarian syndrome), as well as the role of the chemokine SDF1-CXCL12 in human preovulatory follicle in the follow-up of granulosa cell survival and embryo quality in IVF.
ISSN:	0368-2315