Dynamics of pituitary down-regulation and ovarian response to controlled stimulation in in vitro fertilization cycles

The effect of the daily GnRH agonist administration on LH levels and ovarian response after down-regulation was investigated in 2 groups of women who received recombinant FSH versus hMG. The results showed that the pituitary gland remained responsive to the daily buserelin by producing pulses of LH,...

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Veröffentlicht in:	Fertility and sterility 2007-02, Vol.87 (2), p.433-435
Hauptverfasser:	Mohamed, Kamel Abdelhakim, M.R.C.O.G, Davies, W.A.R., F.R.C.O.G, Lashen, Hany, M.D
Format:	Artikel
Sprache:	eng
Schlagworte:	Adult Biological and medical sciences Buserelin - administration & dosage Down-Regulation - drug effects Female Fertilization in Vitro - methods Follicle Stimulating Hormone - administration & dosage Gonadotropin-Releasing Hormone - agonists Gynecology. Andrology. Obstetrics Humans Internal Medicine Luteinizing Hormone - blood Medical sciences Menstrual Cycle - drug effects Menstrual Cycle - physiology Obstetrics and Gynecology Ovulation Induction - methods Pituitary Gland - drug effects Pituitary Gland - metabolism
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Zusammenfassung:	The effect of the daily GnRH agonist administration on LH levels and ovarian response after down-regulation was investigated in 2 groups of women who received recombinant FSH versus hMG. The results showed that the pituitary gland remained responsive to the daily buserelin by producing pulses of LH, despite down-regulation in both groups; however, the patients whose condition is profoundly down-regulated may need exogenous LH to improve their response.
ISSN:	0015-0282 1556-5653
DOI:	10.1016/j.fertnstert.2006.07.1496