Fenretinide and risk reduction of second breast cancer

The authors of this Viewpoint discuss the protective activity of fenretinide on second breast cancer as a surrogate marker of primary prevention and the possibility of using this agent in young women bearing germline BRCA-1 and BRCA-2 mutations.

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Bibliographische Detailangaben
Veröffentlicht in:	Nature clinical practice. Oncology 2007-02, Vol.4 (2), p.64-65
Hauptverfasser:	Decensi, Andrea, Zanardi, Silvia, Argusti, Alessandra, Bonanni, Bernardo, Costa, Alberto, Veronesi, Umberto
Format:	Artikel
Sprache:	eng
Schlagworte:	Adult Aged Anticarcinogenic Agents - therapeutic use Breast cancer Breast Neoplasms - prevention & control Breast Neoplasms - surgery Carcinoma, Intraductal, Noninfiltrating - prevention & control Carcinoma, Intraductal, Noninfiltrating - surgery Dosage and administration Female Fenretinide Fenretinide - therapeutic use Follow-Up Studies Humans Medicine Medicine & Public Health Middle Aged Neoplasms, Second Primary - prevention & control Oncology Prevention Risk factors Treatment Outcome viewpoint
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Beschreibung
Zusammenfassung:	The authors of this Viewpoint discuss the protective activity of fenretinide on second breast cancer as a surrogate marker of primary prevention and the possibility of using this agent in young women bearing germline BRCA-1 and BRCA-2 mutations.
ISSN:	1743-4254 1759-4774 1743-4262 1759-4782
DOI:	10.1038/ncponc0735