Airway Hyperresponsiveness in Patients With Coronary Spastic Angina: Relationship Between Coronary Spasticity and Airway Responsiveness

Background Several reports have suggested a possible link between bronchial asthma and coronary spasm, but the possibility of a relationship in coronary spastic angina (CSA) has not been clarified. Methods and Results Airway responsiveness to methacholine and coronary spasticity to acetylcholine wer...

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Veröffentlicht in:Circulation Journal 2007, Vol.71(2), pp.234-241
Hauptverfasser: Haruta, Shoji, Okayama, Michiko, Uchida, Tatsuro, Hirosawa, Koshichiro, Kasanuki, Hiroshi
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Sprache:eng
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Zusammenfassung:Background Several reports have suggested a possible link between bronchial asthma and coronary spasm, but the possibility of a relationship in coronary spastic angina (CSA) has not been clarified. Methods and Results Airway responsiveness to methacholine and coronary spasticity to acetylcholine were examined in 42 patients with CSA and 36 patients with chest pain syndrome (CP). Furthermore, 18 control subjects were examined and their airway responsiveness compared with that of the CSA and CP patients. The incidence of airway hyperresponsiveness was significantly higher in the CSA group (74%) than in the CP (19%) and control (17%) groups (p
ISSN:1346-9843
1347-4820
DOI:10.1253/circj.71.234