Long QT Syndrome in Adults
Long QT Syndrome in Adults Andrew J. Sauer, Arthur J. Moss, Scott McNitt, Derick R. Peterson, Wojciech Zareba, Jennifer L. Robinson, Ming Qi, Ilan Goldenberg, Jenny B. Hobbs, Michael J. Ackerman, Jesaia Benhorin, W. Jackson Hall, Elizabeth S. Kaufman, Emanuela H. Locati, Carlo Napolitano, MD, Silvia...
Gespeichert in:
| Veröffentlicht in: | Journal of the American College of Cardiology 2007-01, Vol.49 (3), p.329-337 |
|---|---|
| Hauptverfasser: | , , , , , , , , , , , , , , , , , , , |
| Format: | Artikel |
| Sprache: | eng |
| Schlagworte: | |
| Online-Zugang: | Volltext |
| Tags: |
Tag hinzufügen
Keine Tags, Fügen Sie den ersten Tag hinzu!
|
| container_end_page | 337 |
|---|---|
| container_issue | 3 |
| container_start_page | 329 |
| container_title | Journal of the American College of Cardiology |
| container_volume | 49 |
| creator | Sauer, Andrew J., BS Moss, Arthur J., MD McNitt, Scott, MS Peterson, Derick R., PhD Zareba, Wojciech, MD, PhD Robinson, Jennifer L., MS Qi, Ming, PhD Goldenberg, Ilan, MD Hobbs, Jenny B., BA Ackerman, Michael J., MD, PhD Benhorin, Jesaia, MD Hall, W. Jackson, PhD Kaufman, Elizabeth S., MD Locati, Emanuela H., MD, PhD Napolitano, Carlo, MD Priori, Silvia G., MD, PhD Schwartz, Peter J., MD Towbin, Jeffrey A., MD Vincent, G. Michael, MD Zhang, Li, MD |
| description | Long QT Syndrome in Adults Andrew J. Sauer, Arthur J. Moss, Scott McNitt, Derick R. Peterson, Wojciech Zareba, Jennifer L. Robinson, Ming Qi, Ilan Goldenberg, Jenny B. Hobbs, Michael J. Ackerman, Jesaia Benhorin, W. Jackson Hall, Elizabeth S. Kaufman, Emanuela H. Locati, Carlo Napolitano, MD, Silvia G. Priori, Peter J. Schwartz, Jeffrey A. Towbin, G. Michael Vincent, Li Zhang The clinical course and risk factors for cardiac events in genotype-confirmed adult patients with long QT syndrome (LQTS) were investigated. The severity of LQTS in adulthood can be risk stratified with information regarding genotype, gender, corrected QT duration, and history of cardiac events. Beta-blockers effectively reduce but do not eliminate the risk of both syncopal and life-threatening cardiac events in adult patients with mutation-confirmed LQTS. |
| doi_str_mv | 10.1016/j.jacc.2006.08.057 |
| format | Article |
| fullrecord | <record><control><sourceid>proquest_cross</sourceid><recordid>TN_cdi_proquest_miscellaneous_68930857</recordid><sourceformat>XML</sourceformat><sourcesystem>PC</sourcesystem><els_id>1_s2_0_S0735109706026519</els_id><sourcerecordid>3242798991</sourcerecordid><originalsourceid>FETCH-LOGICAL-c545t-f0b9940a98b10ba4a37551c234359b8884003945ee3b0202240a8dc96e5661cf3</originalsourceid><addsrcrecordid>eNp9kU1r3DAQhkVoaLZJ_0AOZaGkNzujT0sQAiH0I7AQQtKzkOVxkOu1E2kd2H9fubuwkENPujzzzqtnCDmnUFKg6rIrO-d9yQBUCboEWR2RBZVSF1ya6gNZQMVlQcFUJ-RTSh1kUFPzkZzQinFTUbEg56txeF4-PC0ft0MTxzUuw7C8aaZ-k87Icev6hJ_37yn5_eP70-2vYnX_8-72ZlV4KeSmaKE2RoAzuqZQO-F4JSX1jIvcotZaCwBuhETkNTBgLLO68UahVIr6lp-Sb7vclzi-Tpg2dh2Sx753A45TskobDlpWGfz6DuzGKQ65m6USFNXCCJYptqN8HFOK2NqXGNYubi0FO3uznZ292dmbBW3hX_SXffRUr7E5jOxFZeBiD7jkXd9GN_iQDpwWUmmuM3e14zAbewsYbfIBB49NiOg3thnD_3tcvxv3fRhC3vgHt5gO_7WJWbCP84XnA4MCpiQ1_C9aTps_</addsrcrecordid><sourcetype>Aggregation Database</sourcetype><iscdi>true</iscdi><recordtype>article</recordtype><pqid>1506184942</pqid></control><display><type>article</type><title>Long QT Syndrome in Adults</title><source>MEDLINE</source><source>Elsevier ScienceDirect Journals</source><source>Elektronische Zeitschriftenbibliothek - Frei zugängliche E-Journals</source><source>Alma/SFX Local Collection</source><creator>Sauer, Andrew J., BS ; Moss, Arthur J., MD ; McNitt, Scott, MS ; Peterson, Derick R., PhD ; Zareba, Wojciech, MD, PhD ; Robinson, Jennifer L., MS ; Qi, Ming, PhD ; Goldenberg, Ilan, MD ; Hobbs, Jenny B., BA ; Ackerman, Michael J., MD, PhD ; Benhorin, Jesaia, MD ; Hall, W. Jackson, PhD ; Kaufman, Elizabeth S., MD ; Locati, Emanuela H., MD, PhD ; Napolitano, Carlo, MD ; Priori, Silvia G., MD, PhD ; Schwartz, Peter J., MD ; Towbin, Jeffrey A., MD ; Vincent, G. Michael, MD ; Zhang, Li, MD</creator><creatorcontrib>Sauer, Andrew J., BS ; Moss, Arthur J., MD ; McNitt, Scott, MS ; Peterson, Derick R., PhD ; Zareba, Wojciech, MD, PhD ; Robinson, Jennifer L., MS ; Qi, Ming, PhD ; Goldenberg, Ilan, MD ; Hobbs, Jenny B., BA ; Ackerman, Michael J., MD, PhD ; Benhorin, Jesaia, MD ; Hall, W. Jackson, PhD ; Kaufman, Elizabeth S., MD ; Locati, Emanuela H., MD, PhD ; Napolitano, Carlo, MD ; Priori, Silvia G., MD, PhD ; Schwartz, Peter J., MD ; Towbin, Jeffrey A., MD ; Vincent, G. Michael, MD ; Zhang, Li, MD</creatorcontrib><description>Long QT Syndrome in Adults Andrew J. Sauer, Arthur J. Moss, Scott McNitt, Derick R. Peterson, Wojciech Zareba, Jennifer L. Robinson, Ming Qi, Ilan Goldenberg, Jenny B. Hobbs, Michael J. Ackerman, Jesaia Benhorin, W. Jackson Hall, Elizabeth S. Kaufman, Emanuela H. Locati, Carlo Napolitano, MD, Silvia G. Priori, Peter J. Schwartz, Jeffrey A. Towbin, G. Michael Vincent, Li Zhang The clinical course and risk factors for cardiac events in genotype-confirmed adult patients with long QT syndrome (LQTS) were investigated. The severity of LQTS in adulthood can be risk stratified with information regarding genotype, gender, corrected QT duration, and history of cardiac events. Beta-blockers effectively reduce but do not eliminate the risk of both syncopal and life-threatening cardiac events in adult patients with mutation-confirmed LQTS.</description><identifier>ISSN: 0735-1097</identifier><identifier>EISSN: 1558-3597</identifier><identifier>DOI: 10.1016/j.jacc.2006.08.057</identifier><identifier>PMID: 17239714</identifier><identifier>CODEN: JACCDI</identifier><language>eng</language><publisher>New York, NY: Elsevier Inc</publisher><subject>Adolescent ; Adrenergic beta-Antagonists - therapeutic use ; Adult ; Age ; Age Distribution ; Biological and medical sciences ; Cardiac dysrhythmias ; Cardiology ; Cardiology. Vascular system ; Cardiovascular ; Child development ; Cohort Studies ; Confidence intervals ; Death, Sudden, Cardiac - epidemiology ; Drug therapy ; Electrocardiography ; Female ; Females ; Gender ; Genes ; Genetic Predisposition to Disease - epidemiology ; Genotype ; Genotype & phenotype ; Heart ; Heart attacks ; Heterozygote ; Humans ; Internal Medicine ; KCNQ1 Potassium Channel - genetics ; Long QT syndrome ; Long QT Syndrome - drug therapy ; Long QT Syndrome - genetics ; Long QT Syndrome - mortality ; Male ; Medical sciences ; Mutation ; Patients ; Population ; Potassium ; Proportional Hazards Models ; Ratios ; Risk Factors ; Severity of Illness Index ; Sex Distribution ; Statistics, Nonparametric ; Studies ; Survival Analysis</subject><ispartof>Journal of the American College of Cardiology, 2007-01, Vol.49 (3), p.329-337</ispartof><rights>American College of Cardiology Foundation</rights><rights>2007 American College of Cardiology Foundation</rights><rights>2007 INIST-CNRS</rights><rights>Copyright Elsevier Limited Jan 23, 2007</rights><lds50>peer_reviewed</lds50><oa>free_for_read</oa><woscitedreferencessubscribed>false</woscitedreferencessubscribed><citedby>FETCH-LOGICAL-c545t-f0b9940a98b10ba4a37551c234359b8884003945ee3b0202240a8dc96e5661cf3</citedby><cites>FETCH-LOGICAL-c545t-f0b9940a98b10ba4a37551c234359b8884003945ee3b0202240a8dc96e5661cf3</cites></display><links><openurl>$$Topenurl_article</openurl><openurlfulltext>$$Topenurlfull_article</openurlfulltext><thumbnail>$$Tsyndetics_thumb_exl</thumbnail><linktohtml>$$Uhttps://dx.doi.org/10.1016/j.jacc.2006.08.057$$EHTML$$P50$$Gelsevier$$Hfree_for_read</linktohtml><link.rule.ids>314,777,781,3537,27905,27906,45976</link.rule.ids><backlink>$$Uhttp://pascal-francis.inist.fr/vibad/index.php?action=getRecordDetail&idt=18456838$$DView record in Pascal Francis$$Hfree_for_read</backlink><backlink>$$Uhttps://www.ncbi.nlm.nih.gov/pubmed/17239714$$D View this record in MEDLINE/PubMed$$Hfree_for_read</backlink></links><search><creatorcontrib>Sauer, Andrew J., BS</creatorcontrib><creatorcontrib>Moss, Arthur J., MD</creatorcontrib><creatorcontrib>McNitt, Scott, MS</creatorcontrib><creatorcontrib>Peterson, Derick R., PhD</creatorcontrib><creatorcontrib>Zareba, Wojciech, MD, PhD</creatorcontrib><creatorcontrib>Robinson, Jennifer L., MS</creatorcontrib><creatorcontrib>Qi, Ming, PhD</creatorcontrib><creatorcontrib>Goldenberg, Ilan, MD</creatorcontrib><creatorcontrib>Hobbs, Jenny B., BA</creatorcontrib><creatorcontrib>Ackerman, Michael J., MD, PhD</creatorcontrib><creatorcontrib>Benhorin, Jesaia, MD</creatorcontrib><creatorcontrib>Hall, W. Jackson, PhD</creatorcontrib><creatorcontrib>Kaufman, Elizabeth S., MD</creatorcontrib><creatorcontrib>Locati, Emanuela H., MD, PhD</creatorcontrib><creatorcontrib>Napolitano, Carlo, MD</creatorcontrib><creatorcontrib>Priori, Silvia G., MD, PhD</creatorcontrib><creatorcontrib>Schwartz, Peter J., MD</creatorcontrib><creatorcontrib>Towbin, Jeffrey A., MD</creatorcontrib><creatorcontrib>Vincent, G. Michael, MD</creatorcontrib><creatorcontrib>Zhang, Li, MD</creatorcontrib><title>Long QT Syndrome in Adults</title><title>Journal of the American College of Cardiology</title><addtitle>J Am Coll Cardiol</addtitle><description>Long QT Syndrome in Adults Andrew J. Sauer, Arthur J. Moss, Scott McNitt, Derick R. Peterson, Wojciech Zareba, Jennifer L. Robinson, Ming Qi, Ilan Goldenberg, Jenny B. Hobbs, Michael J. Ackerman, Jesaia Benhorin, W. Jackson Hall, Elizabeth S. Kaufman, Emanuela H. Locati, Carlo Napolitano, MD, Silvia G. Priori, Peter J. Schwartz, Jeffrey A. Towbin, G. Michael Vincent, Li Zhang The clinical course and risk factors for cardiac events in genotype-confirmed adult patients with long QT syndrome (LQTS) were investigated. The severity of LQTS in adulthood can be risk stratified with information regarding genotype, gender, corrected QT duration, and history of cardiac events. Beta-blockers effectively reduce but do not eliminate the risk of both syncopal and life-threatening cardiac events in adult patients with mutation-confirmed LQTS.</description><subject>Adolescent</subject><subject>Adrenergic beta-Antagonists - therapeutic use</subject><subject>Adult</subject><subject>Age</subject><subject>Age Distribution</subject><subject>Biological and medical sciences</subject><subject>Cardiac dysrhythmias</subject><subject>Cardiology</subject><subject>Cardiology. Vascular system</subject><subject>Cardiovascular</subject><subject>Child development</subject><subject>Cohort Studies</subject><subject>Confidence intervals</subject><subject>Death, Sudden, Cardiac - epidemiology</subject><subject>Drug therapy</subject><subject>Electrocardiography</subject><subject>Female</subject><subject>Females</subject><subject>Gender</subject><subject>Genes</subject><subject>Genetic Predisposition to Disease - epidemiology</subject><subject>Genotype</subject><subject>Genotype & phenotype</subject><subject>Heart</subject><subject>Heart attacks</subject><subject>Heterozygote</subject><subject>Humans</subject><subject>Internal Medicine</subject><subject>KCNQ1 Potassium Channel - genetics</subject><subject>Long QT syndrome</subject><subject>Long QT Syndrome - drug therapy</subject><subject>Long QT Syndrome - genetics</subject><subject>Long QT Syndrome - mortality</subject><subject>Male</subject><subject>Medical sciences</subject><subject>Mutation</subject><subject>Patients</subject><subject>Population</subject><subject>Potassium</subject><subject>Proportional Hazards Models</subject><subject>Ratios</subject><subject>Risk Factors</subject><subject>Severity of Illness Index</subject><subject>Sex Distribution</subject><subject>Statistics, Nonparametric</subject><subject>Studies</subject><subject>Survival Analysis</subject><issn>0735-1097</issn><issn>1558-3597</issn><fulltext>true</fulltext><rsrctype>article</rsrctype><creationdate>2007</creationdate><recordtype>article</recordtype><sourceid>EIF</sourceid><recordid>eNp9kU1r3DAQhkVoaLZJ_0AOZaGkNzujT0sQAiH0I7AQQtKzkOVxkOu1E2kd2H9fubuwkENPujzzzqtnCDmnUFKg6rIrO-d9yQBUCboEWR2RBZVSF1ya6gNZQMVlQcFUJ-RTSh1kUFPzkZzQinFTUbEg56txeF4-PC0ft0MTxzUuw7C8aaZ-k87Icev6hJ_37yn5_eP70-2vYnX_8-72ZlV4KeSmaKE2RoAzuqZQO-F4JSX1jIvcotZaCwBuhETkNTBgLLO68UahVIr6lp-Sb7vclzi-Tpg2dh2Sx753A45TskobDlpWGfz6DuzGKQ65m6USFNXCCJYptqN8HFOK2NqXGNYubi0FO3uznZ292dmbBW3hX_SXffRUr7E5jOxFZeBiD7jkXd9GN_iQDpwWUmmuM3e14zAbewsYbfIBB49NiOg3thnD_3tcvxv3fRhC3vgHt5gO_7WJWbCP84XnA4MCpiQ1_C9aTps_</recordid><startdate>20070123</startdate><enddate>20070123</enddate><creator>Sauer, Andrew J., BS</creator><creator>Moss, Arthur J., MD</creator><creator>McNitt, Scott, MS</creator><creator>Peterson, Derick R., PhD</creator><creator>Zareba, Wojciech, MD, PhD</creator><creator>Robinson, Jennifer L., MS</creator><creator>Qi, Ming, PhD</creator><creator>Goldenberg, Ilan, MD</creator><creator>Hobbs, Jenny B., BA</creator><creator>Ackerman, Michael J., MD, PhD</creator><creator>Benhorin, Jesaia, MD</creator><creator>Hall, W. Jackson, PhD</creator><creator>Kaufman, Elizabeth S., MD</creator><creator>Locati, Emanuela H., MD, PhD</creator><creator>Napolitano, Carlo, MD</creator><creator>Priori, Silvia G., MD, PhD</creator><creator>Schwartz, Peter J., MD</creator><creator>Towbin, Jeffrey A., MD</creator><creator>Vincent, G. Michael, MD</creator><creator>Zhang, Li, MD</creator><general>Elsevier Inc</general><general>Elsevier Science</general><general>Elsevier Limited</general><scope>6I.</scope><scope>AAFTH</scope><scope>IQODW</scope><scope>CGR</scope><scope>CUY</scope><scope>CVF</scope><scope>ECM</scope><scope>EIF</scope><scope>NPM</scope><scope>AAYXX</scope><scope>CITATION</scope><scope>7T5</scope><scope>7TK</scope><scope>H94</scope><scope>K9.</scope><scope>NAPCQ</scope><scope>7X8</scope></search><sort><creationdate>20070123</creationdate><title>Long QT Syndrome in Adults</title><author>Sauer, Andrew J., BS ; Moss, Arthur J., MD ; McNitt, Scott, MS ; Peterson, Derick R., PhD ; Zareba, Wojciech, MD, PhD ; Robinson, Jennifer L., MS ; Qi, Ming, PhD ; Goldenberg, Ilan, MD ; Hobbs, Jenny B., BA ; Ackerman, Michael J., MD, PhD ; Benhorin, Jesaia, MD ; Hall, W. Jackson, PhD ; Kaufman, Elizabeth S., MD ; Locati, Emanuela H., MD, PhD ; Napolitano, Carlo, MD ; Priori, Silvia G., MD, PhD ; Schwartz, Peter J., MD ; Towbin, Jeffrey A., MD ; Vincent, G. Michael, MD ; Zhang, Li, MD</author></sort><facets><frbrtype>5</frbrtype><frbrgroupid>cdi_FETCH-LOGICAL-c545t-f0b9940a98b10ba4a37551c234359b8884003945ee3b0202240a8dc96e5661cf3</frbrgroupid><rsrctype>articles</rsrctype><prefilter>articles</prefilter><language>eng</language><creationdate>2007</creationdate><topic>Adolescent</topic><topic>Adrenergic beta-Antagonists - therapeutic use</topic><topic>Adult</topic><topic>Age</topic><topic>Age Distribution</topic><topic>Biological and medical sciences</topic><topic>Cardiac dysrhythmias</topic><topic>Cardiology</topic><topic>Cardiology. Vascular system</topic><topic>Cardiovascular</topic><topic>Child development</topic><topic>Cohort Studies</topic><topic>Confidence intervals</topic><topic>Death, Sudden, Cardiac - epidemiology</topic><topic>Drug therapy</topic><topic>Electrocardiography</topic><topic>Female</topic><topic>Females</topic><topic>Gender</topic><topic>Genes</topic><topic>Genetic Predisposition to Disease - epidemiology</topic><topic>Genotype</topic><topic>Genotype & phenotype</topic><topic>Heart</topic><topic>Heart attacks</topic><topic>Heterozygote</topic><topic>Humans</topic><topic>Internal Medicine</topic><topic>KCNQ1 Potassium Channel - genetics</topic><topic>Long QT syndrome</topic><topic>Long QT Syndrome - drug therapy</topic><topic>Long QT Syndrome - genetics</topic><topic>Long QT Syndrome - mortality</topic><topic>Male</topic><topic>Medical sciences</topic><topic>Mutation</topic><topic>Patients</topic><topic>Population</topic><topic>Potassium</topic><topic>Proportional Hazards Models</topic><topic>Ratios</topic><topic>Risk Factors</topic><topic>Severity of Illness Index</topic><topic>Sex Distribution</topic><topic>Statistics, Nonparametric</topic><topic>Studies</topic><topic>Survival Analysis</topic><toplevel>peer_reviewed</toplevel><toplevel>online_resources</toplevel><creatorcontrib>Sauer, Andrew J., BS</creatorcontrib><creatorcontrib>Moss, Arthur J., MD</creatorcontrib><creatorcontrib>McNitt, Scott, MS</creatorcontrib><creatorcontrib>Peterson, Derick R., PhD</creatorcontrib><creatorcontrib>Zareba, Wojciech, MD, PhD</creatorcontrib><creatorcontrib>Robinson, Jennifer L., MS</creatorcontrib><creatorcontrib>Qi, Ming, PhD</creatorcontrib><creatorcontrib>Goldenberg, Ilan, MD</creatorcontrib><creatorcontrib>Hobbs, Jenny B., BA</creatorcontrib><creatorcontrib>Ackerman, Michael J., MD, PhD</creatorcontrib><creatorcontrib>Benhorin, Jesaia, MD</creatorcontrib><creatorcontrib>Hall, W. Jackson, PhD</creatorcontrib><creatorcontrib>Kaufman, Elizabeth S., MD</creatorcontrib><creatorcontrib>Locati, Emanuela H., MD, PhD</creatorcontrib><creatorcontrib>Napolitano, Carlo, MD</creatorcontrib><creatorcontrib>Priori, Silvia G., MD, PhD</creatorcontrib><creatorcontrib>Schwartz, Peter J., MD</creatorcontrib><creatorcontrib>Towbin, Jeffrey A., MD</creatorcontrib><creatorcontrib>Vincent, G. Michael, MD</creatorcontrib><creatorcontrib>Zhang, Li, MD</creatorcontrib><collection>ScienceDirect Open Access Titles</collection><collection>Elsevier:ScienceDirect:Open Access</collection><collection>Pascal-Francis</collection><collection>Medline</collection><collection>MEDLINE</collection><collection>MEDLINE (Ovid)</collection><collection>MEDLINE</collection><collection>MEDLINE</collection><collection>PubMed</collection><collection>CrossRef</collection><collection>Immunology Abstracts</collection><collection>Neurosciences Abstracts</collection><collection>AIDS and Cancer Research Abstracts</collection><collection>ProQuest Health & Medical Complete (Alumni)</collection><collection>Nursing & Allied Health Premium</collection><collection>MEDLINE - Academic</collection><jtitle>Journal of the American College of Cardiology</jtitle></facets><delivery><delcategory>Remote Search Resource</delcategory><fulltext>fulltext</fulltext></delivery><addata><au>Sauer, Andrew J., BS</au><au>Moss, Arthur J., MD</au><au>McNitt, Scott, MS</au><au>Peterson, Derick R., PhD</au><au>Zareba, Wojciech, MD, PhD</au><au>Robinson, Jennifer L., MS</au><au>Qi, Ming, PhD</au><au>Goldenberg, Ilan, MD</au><au>Hobbs, Jenny B., BA</au><au>Ackerman, Michael J., MD, PhD</au><au>Benhorin, Jesaia, MD</au><au>Hall, W. Jackson, PhD</au><au>Kaufman, Elizabeth S., MD</au><au>Locati, Emanuela H., MD, PhD</au><au>Napolitano, Carlo, MD</au><au>Priori, Silvia G., MD, PhD</au><au>Schwartz, Peter J., MD</au><au>Towbin, Jeffrey A., MD</au><au>Vincent, G. Michael, MD</au><au>Zhang, Li, MD</au><format>journal</format><genre>article</genre><ristype>JOUR</ristype><atitle>Long QT Syndrome in Adults</atitle><jtitle>Journal of the American College of Cardiology</jtitle><addtitle>J Am Coll Cardiol</addtitle><date>2007-01-23</date><risdate>2007</risdate><volume>49</volume><issue>3</issue><spage>329</spage><epage>337</epage><pages>329-337</pages><issn>0735-1097</issn><eissn>1558-3597</eissn><coden>JACCDI</coden><abstract>Long QT Syndrome in Adults Andrew J. Sauer, Arthur J. Moss, Scott McNitt, Derick R. Peterson, Wojciech Zareba, Jennifer L. Robinson, Ming Qi, Ilan Goldenberg, Jenny B. Hobbs, Michael J. Ackerman, Jesaia Benhorin, W. Jackson Hall, Elizabeth S. Kaufman, Emanuela H. Locati, Carlo Napolitano, MD, Silvia G. Priori, Peter J. Schwartz, Jeffrey A. Towbin, G. Michael Vincent, Li Zhang The clinical course and risk factors for cardiac events in genotype-confirmed adult patients with long QT syndrome (LQTS) were investigated. The severity of LQTS in adulthood can be risk stratified with information regarding genotype, gender, corrected QT duration, and history of cardiac events. Beta-blockers effectively reduce but do not eliminate the risk of both syncopal and life-threatening cardiac events in adult patients with mutation-confirmed LQTS.</abstract><cop>New York, NY</cop><pub>Elsevier Inc</pub><pmid>17239714</pmid><doi>10.1016/j.jacc.2006.08.057</doi><tpages>9</tpages><oa>free_for_read</oa></addata></record> |
| fulltext | fulltext |
| identifier | ISSN: 0735-1097 |
| ispartof | Journal of the American College of Cardiology, 2007-01, Vol.49 (3), p.329-337 |
| issn | 0735-1097 1558-3597 |
| language | eng |
| recordid | cdi_proquest_miscellaneous_68930857 |
| source | MEDLINE; Elsevier ScienceDirect Journals; Elektronische Zeitschriftenbibliothek - Frei zugängliche E-Journals; Alma/SFX Local Collection |
| subjects | Adolescent Adrenergic beta-Antagonists - therapeutic use Adult Age Age Distribution Biological and medical sciences Cardiac dysrhythmias Cardiology Cardiology. Vascular system Cardiovascular Child development Cohort Studies Confidence intervals Death, Sudden, Cardiac - epidemiology Drug therapy Electrocardiography Female Females Gender Genes Genetic Predisposition to Disease - epidemiology Genotype Genotype & phenotype Heart Heart attacks Heterozygote Humans Internal Medicine KCNQ1 Potassium Channel - genetics Long QT syndrome Long QT Syndrome - drug therapy Long QT Syndrome - genetics Long QT Syndrome - mortality Male Medical sciences Mutation Patients Population Potassium Proportional Hazards Models Ratios Risk Factors Severity of Illness Index Sex Distribution Statistics, Nonparametric Studies Survival Analysis |
| title | Long QT Syndrome in Adults |
| url | https://sfx.bib-bvb.de/sfx_tum?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&ctx_tim=2025-01-19T12%3A30%3A40IST&url_ver=Z39.88-2004&url_ctx_fmt=infofi/fmt:kev:mtx:ctx&rfr_id=info:sid/primo.exlibrisgroup.com:primo3-Article-proquest_cross&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=article&rft.atitle=Long%20QT%20Syndrome%20in%20Adults&rft.jtitle=Journal%20of%20the%20American%20College%20of%20Cardiology&rft.au=Sauer,%20Andrew%20J.,%20BS&rft.date=2007-01-23&rft.volume=49&rft.issue=3&rft.spage=329&rft.epage=337&rft.pages=329-337&rft.issn=0735-1097&rft.eissn=1558-3597&rft.coden=JACCDI&rft_id=info:doi/10.1016/j.jacc.2006.08.057&rft_dat=%3Cproquest_cross%3E3242798991%3C/proquest_cross%3E%3Curl%3E%3C/url%3E&disable_directlink=true&sfx.directlink=off&sfx.report_link=0&rft_id=info:oai/&rft_pqid=1506184942&rft_id=info:pmid/17239714&rft_els_id=1_s2_0_S0735109706026519&rfr_iscdi=true |