Increased preoperative serum C‐reactive protein level predicts a poor prognosis in patients with localized renal cell carcinoma

OBJECTIVE To evaluate the value of the preoperative serum C‐reactive protein (CRP) level in the prognosis of patients with localized renal cell carcinoma (RCC). PATIENTS AND METHODS The study comprised 101 patients who had a radical nephrectomy for localized RCC (pT1–3N0M0). An elevated CRP was defi...

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Veröffentlicht in:BJU international 2007-01, Vol.99 (1), p.77-80
Hauptverfasser: KOMAI, YOSHINOBU, SAITO, KAZUTAKA, SAKAI, KUNIHIKO, MORIMOTO, SHINJI
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Sprache:eng
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Zusammenfassung:OBJECTIVE To evaluate the value of the preoperative serum C‐reactive protein (CRP) level in the prognosis of patients with localized renal cell carcinoma (RCC). PATIENTS AND METHODS The study comprised 101 patients who had a radical nephrectomy for localized RCC (pT1–3N0M0). An elevated CRP was defined as >0.5 mg/dL before surgery. Survival rates for each variant were calculated using the Kaplan–Meier method, with the difference between survival curves evaluated using the log‐rank test. Multivariate analysis was by Cox proportional hazard model; for all analyses the difference was considered significant when P 
ISSN:1464-4096
1464-410X
DOI:10.1111/j.1464-410X.2006.06497.x