Inherited myopathy in a young Great Dane

A 3-year-old, male Great Dane was evaluated for an 18-month history of progressive weakness. Histologic evaluation of muscle biopsies revealed distinct cytoarchitectural changes that were indistinguishable from the central "core-like" structures previously described as central core myopath...

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Veröffentlicht in:	Canadian veterinary journal 2006-09, Vol.47 (9), p.891-893
Hauptverfasser:	McMillan, C.J, Taylor, S.M, Shelton, G.D
Format:	Artikel
Sprache:	eng
Schlagworte:	Animals Biopsy - veterinary case studies congenital abnormalities disease diagnosis dog diseases Dog Diseases - congenital Dog Diseases - diagnosis Dog Diseases - pathology Dogs Genetic Predisposition to Disease Great Dane Male Muscle, Skeletal - pathology muscular diseases Myopathy, Central Core - congenital Myopathy, Central Core - diagnosis Myopathy, Central Core - pathology Myopathy, Central Core - veterinary signs and symptoms (animals and humans)
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Beschreibung
Zusammenfassung:	A 3-year-old, male Great Dane was evaluated for an 18-month history of progressive weakness. Histologic evaluation of muscle biopsies revealed distinct cytoarchitectural changes that were indistinguishable from the central "core-like" structures previously described as central core myopathy in this breed. Clinical features of this inherited myopathy are described.
ISSN:	0008-5286