Significance of apoptosis in prostatic intraepithelial neoplasia and carcinoma

This study was carried out to assess the significance of apoptosis in prostatic intraepithelial neoplasia (PIN) and prostate cancer. A total of 120 prostatic specimens were studied in the department of Pathology [corrected] JNMC, Aligarh. The rate of apoptosis in PIN and prostate cancer was examined...

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Veröffentlicht in:Indian journal of pathology & microbiology 2005-10, Vol.48 (4), p.444-447
Hauptverfasser: Sherwani, Rana, Khan, Sabina, Khan, Nazoora, Kamran, Mohd, Husain, Musharraf
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container_title Indian journal of pathology & microbiology
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creator Sherwani, Rana
Khan, Sabina
Khan, Nazoora
Kamran, Mohd
Husain, Musharraf
description This study was carried out to assess the significance of apoptosis in prostatic intraepithelial neoplasia (PIN) and prostate cancer. A total of 120 prostatic specimens were studied in the department of Pathology [corrected] JNMC, Aligarh. The rate of apoptosis in PIN and prostate cancer was examined by quantifying the number of apoptotic bodies per hundred cells (apoptotic index) on haematoxylin and eosin stained histological sections [corrected] A significant correlation was noted between increasing apoptotic indices and increasing Gleason grades within a cancer.
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subjects Aged
Apoptosis
Humans
Male
Middle Aged
Prostatic Hyperplasia - pathology
Prostatic Intraepithelial Neoplasia - pathology
Prostatic Neoplasms - pathology
title Significance of apoptosis in prostatic intraepithelial neoplasia and carcinoma
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