Significance of apoptosis in prostatic intraepithelial neoplasia and carcinoma

This study was carried out to assess the significance of apoptosis in prostatic intraepithelial neoplasia (PIN) and prostate cancer. A total of 120 prostatic specimens were studied in the department of Pathology [corrected] JNMC, Aligarh. The rate of apoptosis in PIN and prostate cancer was examined...

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Veröffentlicht in:	Indian journal of pathology & microbiology 2005-10, Vol.48 (4), p.444-447
Hauptverfasser:	Sherwani, Rana, Khan, Sabina, Khan, Nazoora, Kamran, Mohd, Husain, Musharraf
Format:	Artikel
Sprache:	eng
Schlagworte:	Aged Apoptosis Humans Male Middle Aged Prostatic Hyperplasia - pathology Prostatic Intraepithelial Neoplasia - pathology Prostatic Neoplasms - pathology
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Zusammenfassung:	This study was carried out to assess the significance of apoptosis in prostatic intraepithelial neoplasia (PIN) and prostate cancer. A total of 120 prostatic specimens were studied in the department of Pathology [corrected] JNMC, Aligarh. The rate of apoptosis in PIN and prostate cancer was examined by quantifying the number of apoptotic bodies per hundred cells (apoptotic index) on haematoxylin and eosin stained histological sections [corrected] A significant correlation was noted between increasing apoptotic indices and increasing Gleason grades within a cancer.
ISSN:	0377-4929