Spectrally Resolved Magnetic Resonance Imaging of a Xenon Biosensor

Spectrally Resolved Magnetic Resonance Imaging of a Xenon Biosensor

Going hyper: A continuous flow of water saturated with hyperpolarized xenon through a glass tube assembly containing a xenon biosensor attached through its biotin tag to immobilized avidin–agarose beads (see picture) packed in between two frits results in distinct NMR signals that allow detection of...

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Veröffentlicht in:Angewandte Chemie International Edition 2005-12, Vol.45 (1), p.70-73
Hauptverfasser: Hilty, Christian, Lowery, Thomas J., Wemmer, David E., Pines, Alexander
Format: Artikel
Sprache:eng
Schlagworte:
Biosensing Techniques - instrumentation
Biosensing Techniques - methods
biosensors
cage compounds
imaging agents
Magnetic Resonance Imaging
Molecular Structure
xenon
Xenon - analysis
Xenon - chemistry
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Zusammenfassung:Going hyper: A continuous flow of water saturated with hyperpolarized xenon through a glass tube assembly containing a xenon biosensor attached through its biotin tag to immobilized avidin–agarose beads (see picture) packed in between two frits results in distinct NMR signals that allow detection of the immobilized avidin analyte with high sensitivity.
ISSN:1433-7851
1521-3773
DOI:10.1002/anie.200502693