Effect of ghrelin on activities of some lysosomal hydrolases in rabbits

Observing the changes of activity of some lysosomal enzymes in blood serum of female rabbits subjected to injection of 10 microg of ghrelin/kg of body weight. In the blood serum the activity of cathepsins D and L, alanine aminopeptidase, acid phosphatase, lysosomal lipase and lysosomal esterase was...

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Veröffentlicht in:	Neuro-endocrinology letters 2005-08, Vol.26 (4), p.397-400
Hauptverfasser:	Witek, Bozena, Ochwanowska, Ewa, Rafay, Jan, Kolataj, Adam, Chrenek, Peter, Suvegova, Karin, Jurcik, Rastislav, Sirotkin, Alexander, Darlak, Krzysztof
Format:	Artikel
Sprache:	eng
Schlagworte:	Acid Phosphatase - blood Animals Cathepsin D - blood Cathepsin L Cathepsins - blood CD13 Antigens - blood Cysteine Endopeptidases - blood Esterases - blood Female Ghrelin Homeostasis - drug effects Homeostasis - physiology Hydrolases - blood Lipase - blood Lysosomes - enzymology Peptide Hormones - pharmacology Rabbits
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Zusammenfassung:	Observing the changes of activity of some lysosomal enzymes in blood serum of female rabbits subjected to injection of 10 microg of ghrelin/kg of body weight. In the blood serum the activity of cathepsins D and L, alanine aminopeptidase, acid phosphatase, lysosomal lipase and lysosomal esterase was determined. As a result of ghrelin injection the activity of all the enzymes examined in blood serum increased markedly. Changes of lysosomal enzymes activities in the blood serum caused by the effects of ghrelin should be regarded as the response of the lysosomal system.
ISSN:	0172-780X