Self-Assembly of DNA Double-Double Crossover Complexes into High-Density, Doubly Connected, Planar Structures

We designed a molecular complex, the double−double crossover, consisting of four DNA double helices connected by six reciprocal exchanges. Atomic force micrographs suggest that double−double crossover complexes self-assemble into high-density, doubly connected, two-dimensional, planar structures. Such structures may be suitable as substrates for the deposition of nanomaterials in the creation of high-density electrical and quantum devices. We speculate about a modified double−double crossover complex that might self-assemble into high-density, doubly connected, three-dimensional structures.