Low Plasma Taurine Concentration in Newfoundland Dogs is Associated with Low Plasma Methionine and Cyst(e)ine Concentrations and Low Taurine Synthesis
Although taurine is not dietarily essential for dogs, taurine deficiency and dilated cardiomyopathy (DCM) are sporadically reported in large-breed dogs. Taurine status and husbandry were examined in 216 privately owned Newfoundlands, a giant dog breed with high incidence of idiopathic DCM (1.3-2.5%)...
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Veröffentlicht in: | The Journal of nutrition 2006-10, Vol.136 (10), p.2525-2533 |
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Sprache: | eng |
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Zusammenfassung: | Although taurine is not dietarily essential for dogs, taurine deficiency and dilated cardiomyopathy (DCM) are sporadically reported in large-breed dogs. Taurine status and husbandry were examined in 216 privately owned Newfoundlands, a giant dog breed with high incidence of idiopathic DCM (1.3-2.5%). Plasma taurine concentration was positively correlated (P < 0.01) with plasma cyst(e)ine (r = 0.37) and methionine (r = 0.35) concentrations and was similar across age, sex, neutering status, body weight, and body-condition scores. Plasma taurine concentration was low (-0.75 · d-1), and greater (P < 0.05) fecal bile acid excretion (1.7 ± 0.2 vs. 1.4 ± 0.2 μmol/g). Newfoundlands would appear to have a higher dietary sulfur amino acid requirement than Beagles, a model breed used in nutrient requirement determinations. |
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ISSN: | 0022-3166 1541-6100 |
DOI: | 10.1093/jn/136.10.2525 |