Fluorinated Phosphonates: Synthesis and Biomedical Application

The chemistry of fluorinated alykylphosphonates is a relatively new area of research, developed mostly over the last two decades. The synthesis, fundamental chemical properties, and biomedical uses of the phosphonic acid derivatives that bear at least one fluorine substituent on the organyl moiety a...

Ausführliche Beschreibung

Gespeichert in:

Bibliographische Detailangaben
Veröffentlicht in:	Chemical reviews 2006-09, Vol.106 (9), p.3868-3935
Hauptverfasser:	Romanenko, Vadim D, Kukhar, Valery P
Format:	Artikel
Sprache:	eng
Schlagworte:	Antibodies - chemistry Antineoplastic Agents - chemical synthesis Antineoplastic Agents - chemistry Antineoplastic Agents - pharmacology Antiviral Agents - chemical synthesis Antiviral Agents - chemistry Antiviral Agents - pharmacology Biomedical research Catalysis Chemical synthesis Chemistry Enzyme Inhibitors - chemical synthesis Enzyme Inhibitors - chemistry Enzyme Inhibitors - pharmacology Hydrocarbons, Fluorinated - chemistry Inhibitor drugs Molecular Structure Organophosphonates - chemical synthesis Organophosphonates - chemistry Organophosphonates - pharmacology Platelet Aggregation Inhibitors - chemical synthesis Platelet Aggregation Inhibitors - chemistry Platelet Aggregation Inhibitors - pharmacology Stereoisomerism
Online-Zugang:	Volltext
Tags:	Tag hinzufügen Keine Tags, Fügen Sie den ersten Tag hinzu!

Beschreibung
Zusammenfassung:	The chemistry of fluorinated alykylphosphonates is a relatively new area of research, developed mostly over the last two decades. The synthesis, fundamental chemical properties, and biomedical uses of the phosphonic acid derivatives that bear at least one fluorine substituent on the organyl moiety are the subject of this review.
ISSN:	0009-2665 1520-6890
DOI:	10.1021/cr051000q