Increased cardiovascular risk profile and mortality in kidney allograft recipients with post-transplant diabetes mellitus in Spain

:  Background:  Post‐transplant diabetes mellitus (PTDM) is associated with poorer outcomes in kidney transplantation (KT) but little information exists about the evolution of traditional cardiovascular risk (CVR) factors under this disorder. Methods:  We retrospectively analysed CVR factors at 3, 1...

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Veröffentlicht in:Clinical transplantation 2006-09, Vol.20 (5), p.650-658
Hauptverfasser: González-Posada, José Manuel, Hernández, Domingo, Genís, Beatriz Bayés, Tamajón, Lourdes Perez, Pérez, Javier García, Maceira, Benito, Sánchez, Manuel Rivero, Serón, Daniel
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Sprache:eng
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Zusammenfassung::  Background:  Post‐transplant diabetes mellitus (PTDM) is associated with poorer outcomes in kidney transplantation (KT) but little information exists about the evolution of traditional cardiovascular risk (CVR) factors under this disorder. Methods:  We retrospectively analysed CVR factors at 3, 12 and 24 months of follow‐up and mortality at three yr in 3365 KT performed in Spain during the years 1990, 1994 and 1998 with a functioning graft after the first year. Three groups were considered: (i) (PTDM, n, 251), (ii) diabetes mellitus as primary disease (DM, n = 156) and (iii) the remaining patients (controls, n = 2958). Results:  Recipient age, weight and body mass index (BMI) were higher in PTDM than in the other groups (p 
ISSN:0902-0063
1399-0012
DOI:10.1111/j.1399-0012.2006.00532.x