Antibiotic Susceptibility and Molecular Diversity of Bacillus anthracis Strains in Chad: Detection of a New Phylogenetic Subgroup

We genotyped 15 Bacillus anthracis isolates from Chad, Africa, using multiple-locus variable-number tandem repeat analysis and three additional direct-repeat markers. We identified two unique genotypes that represent a novel genetic lineage in the A cluster. Chadian isolates were susceptible to 11 a...

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Veröffentlicht in:	Journal of Clinical Microbiology 2006-09, Vol.44 (9), p.3422-3425
Hauptverfasser:	Maho, Angaya, Rossano, Alexandra, Hächler, Herbert, Holzer, Anita, Schelling, Esther, Zinsstag, Jakob, Hassane, Mahamat H, Toguebaye, Bhen S, Akakpo, Ayayi J, Van Ert, Matthew, Keim, Paul, Kenefic, Leo, Frey, Joachim, Perreten, Vincent
Format:	Artikel
Sprache:	eng
Schlagworte:	Anthrax - microbiology Anti-Bacterial Agents - pharmacology Bacillus anthracis Bacillus anthracis - classification Bacillus anthracis - drug effects Bacillus anthracis - genetics Bacteriology Biological and medical sciences Chad Fundamental and applied biological sciences. Psychology Genetic Variation Genotype Humans Infectious diseases Medical sciences Microbial Sensitivity Tests Microbiology Minisatellite Repeats - genetics Phylogeny Polymerase Chain Reaction Repetitive Sequences, Nucleic Acid
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Zusammenfassung:	We genotyped 15 Bacillus anthracis isolates from Chad, Africa, using multiple-locus variable-number tandem repeat analysis and three additional direct-repeat markers. We identified two unique genotypes that represent a novel genetic lineage in the A cluster. Chadian isolates were susceptible to 11 antibiotics and free of 94 antibiotic resistance genes.
ISSN:	0095-1137 1098-660X 1098-5530
DOI:	10.1128/JCM.01269-06