Effectiveness of treating ovarian hyperstimulation syndrome with cabergoline in two patients with gonadotropin-producing pituitary adenomas
To report the effect of cabergoline on ovarian hyperstimulation syndrome associated with gonadotropin-secreting pituitary adenomas. Case report. Outpatient practice. Two women with menstrual irregularity, enlarged ovaries, high E2, and normal gonadotropin levels. Cabergoline treatment and transsphen...
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| Veröffentlicht in: | Fertility and sterility 2006-09, Vol.86 (3), p.719.e15-719.e18 |
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| creator | Knoepfelmacher, Mirta Danilovic, Debora L.S. Rosa Nasser, Rubia H.R. Mendonça, Berenice B. |
| description | To report the effect of cabergoline on ovarian hyperstimulation syndrome associated with gonadotropin-secreting pituitary adenomas.
Case report.
Outpatient practice.
Two women with menstrual irregularity, enlarged ovaries, high E2, and normal gonadotropin levels.
Cabergoline treatment and transsphenoidal surgery.
Estradiol levels, transvaginal ultrasonography, and pituitary magnetic resonance imaging. Transsphenoidal surgery showed pituitary adenoma staining for LH in both patients.
Cabergoline was effective in reducing E2 levels and decreasing ovarian size but ineffective in shrinking the pituitary adenomas.
This is the first description of the effectiveness of cabergoline as the primary treatment of spontaneous ovarian hyperstimulation syndrome in patients with gonadotropin-producing pituitary adenomas. |
| doi_str_mv | 10.1016/j.fertnstert.2006.01.055 |
| format | Article |
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Case report.
Outpatient practice.
Two women with menstrual irregularity, enlarged ovaries, high E2, and normal gonadotropin levels.
Cabergoline treatment and transsphenoidal surgery.
Estradiol levels, transvaginal ultrasonography, and pituitary magnetic resonance imaging. Transsphenoidal surgery showed pituitary adenoma staining for LH in both patients.
Cabergoline was effective in reducing E2 levels and decreasing ovarian size but ineffective in shrinking the pituitary adenomas.
This is the first description of the effectiveness of cabergoline as the primary treatment of spontaneous ovarian hyperstimulation syndrome in patients with gonadotropin-producing pituitary adenomas.</description><identifier>ISSN: 0015-0282</identifier><identifier>EISSN: 1556-5653</identifier><identifier>DOI: 10.1016/j.fertnstert.2006.01.055</identifier><identifier>PMID: 16952513</identifier><language>eng</language><publisher>United States: Elsevier Inc</publisher><subject>Adenoma ; Adult ; Antineoplastic Agents - therapeutic use ; cabergoline ; Ergolines - therapeutic use ; Female ; Gonadotropin-secreting pituitary adenoma ; Gonadotropins - metabolism ; Humans ; Ovarian Hyperstimulation Syndrome - complications ; Ovarian Hyperstimulation Syndrome - drug therapy ; Ovarian Hyperstimulation Syndrome - metabolism ; Pituitary Neoplasms - complications ; Pituitary Neoplasms - drug therapy ; Pituitary Neoplasms - metabolism ; spontaneous ovarian hyperstimulation syndrome</subject><ispartof>Fertility and sterility, 2006-09, Vol.86 (3), p.719.e15-719.e18</ispartof><rights>2006 American Society for Reproductive Medicine</rights><lds50>peer_reviewed</lds50><oa>free_for_read</oa><woscitedreferencessubscribed>false</woscitedreferencessubscribed><citedby>FETCH-LOGICAL-c422t-f9572fc57d1b0fc63dfca627ae588ea19edacc349c4bfb733638dc32f41188163</citedby><cites>FETCH-LOGICAL-c422t-f9572fc57d1b0fc63dfca627ae588ea19edacc349c4bfb733638dc32f41188163</cites></display><links><openurl>$$Topenurl_article</openurl><openurlfulltext>$$Topenurlfull_article</openurlfulltext><thumbnail>$$Tsyndetics_thumb_exl</thumbnail><linktohtml>$$Uhttps://www.sciencedirect.com/science/article/pii/S0015028206010181$$EHTML$$P50$$Gelsevier$$Hfree_for_read</linktohtml><link.rule.ids>314,776,780,3537,27901,27902,65534</link.rule.ids><backlink>$$Uhttps://www.ncbi.nlm.nih.gov/pubmed/16952513$$D View this record in MEDLINE/PubMed$$Hfree_for_read</backlink></links><search><creatorcontrib>Knoepfelmacher, Mirta</creatorcontrib><creatorcontrib>Danilovic, Debora L.S.</creatorcontrib><creatorcontrib>Rosa Nasser, Rubia H.R.</creatorcontrib><creatorcontrib>Mendonça, Berenice B.</creatorcontrib><title>Effectiveness of treating ovarian hyperstimulation syndrome with cabergoline in two patients with gonadotropin-producing pituitary adenomas</title><title>Fertility and sterility</title><addtitle>Fertil Steril</addtitle><description>To report the effect of cabergoline on ovarian hyperstimulation syndrome associated with gonadotropin-secreting pituitary adenomas.
Case report.
Outpatient practice.
Two women with menstrual irregularity, enlarged ovaries, high E2, and normal gonadotropin levels.
Cabergoline treatment and transsphenoidal surgery.
Estradiol levels, transvaginal ultrasonography, and pituitary magnetic resonance imaging. Transsphenoidal surgery showed pituitary adenoma staining for LH in both patients.
Cabergoline was effective in reducing E2 levels and decreasing ovarian size but ineffective in shrinking the pituitary adenomas.
This is the first description of the effectiveness of cabergoline as the primary treatment of spontaneous ovarian hyperstimulation syndrome in patients with gonadotropin-producing pituitary adenomas.</description><subject>Adenoma</subject><subject>Adult</subject><subject>Antineoplastic Agents - therapeutic use</subject><subject>cabergoline</subject><subject>Ergolines - therapeutic use</subject><subject>Female</subject><subject>Gonadotropin-secreting pituitary adenoma</subject><subject>Gonadotropins - metabolism</subject><subject>Humans</subject><subject>Ovarian Hyperstimulation Syndrome - complications</subject><subject>Ovarian Hyperstimulation Syndrome - drug therapy</subject><subject>Ovarian Hyperstimulation Syndrome - metabolism</subject><subject>Pituitary Neoplasms - complications</subject><subject>Pituitary Neoplasms - drug therapy</subject><subject>Pituitary Neoplasms - metabolism</subject><subject>spontaneous ovarian hyperstimulation syndrome</subject><issn>0015-0282</issn><issn>1556-5653</issn><fulltext>true</fulltext><rsrctype>article</rsrctype><creationdate>2006</creationdate><recordtype>article</recordtype><sourceid>EIF</sourceid><recordid>eNqFkc1u3CAQgFHVKNkmeYWKU292AS8YH9soaStF6qU9IwzDhpUNLuCN9hn60mW1K-XYy3CYb36YDyFMSUsJFZ_3rYNUQi41towQ0RLaEs7foQ3lXDRc8O492hBCeUOYZDfoQ857UkHas2t0Q8XAGafdBv19dA5M8QcIkDOODpcEuviww_Ggk9cBvxwXSLn4eZ1qIgacj8GmOAN-9eUFGz1C2sXJB8A-4PIa8VI5CCWfgV0M2saS4uJDs6RoV3Nqv_iy-qLTEWsLIc4636Erp6cM95f3Fv1-evz18L15_vntx8OX58ZsGSuNG3jPnOG9pSNxRnTWGS1Yr4FLCZoOYLUx3XYw29GNfdeJTlrTMbelVEoqulv06dy3LvNnhVzU7LOBadIB4pqVkJJRNgwVlGfQpJhzAqeW5Oe6sqJEnUSovXoToU4iFKGqiqilHy8z1nEG-1Z4uXwFvp4BqD89eEgqm3o0A9anKkTZ6P8_5R9IDKVn</recordid><startdate>20060901</startdate><enddate>20060901</enddate><creator>Knoepfelmacher, Mirta</creator><creator>Danilovic, Debora L.S.</creator><creator>Rosa Nasser, Rubia H.R.</creator><creator>Mendonça, Berenice B.</creator><general>Elsevier Inc</general><scope>6I.</scope><scope>AAFTH</scope><scope>CGR</scope><scope>CUY</scope><scope>CVF</scope><scope>ECM</scope><scope>EIF</scope><scope>NPM</scope><scope>AAYXX</scope><scope>CITATION</scope><scope>7X8</scope></search><sort><creationdate>20060901</creationdate><title>Effectiveness of treating ovarian hyperstimulation syndrome with cabergoline in two patients with gonadotropin-producing pituitary adenomas</title><author>Knoepfelmacher, Mirta ; Danilovic, Debora L.S. ; Rosa Nasser, Rubia H.R. ; Mendonça, Berenice B.</author></sort><facets><frbrtype>5</frbrtype><frbrgroupid>cdi_FETCH-LOGICAL-c422t-f9572fc57d1b0fc63dfca627ae588ea19edacc349c4bfb733638dc32f41188163</frbrgroupid><rsrctype>articles</rsrctype><prefilter>articles</prefilter><language>eng</language><creationdate>2006</creationdate><topic>Adenoma</topic><topic>Adult</topic><topic>Antineoplastic Agents - therapeutic use</topic><topic>cabergoline</topic><topic>Ergolines - therapeutic use</topic><topic>Female</topic><topic>Gonadotropin-secreting pituitary adenoma</topic><topic>Gonadotropins - metabolism</topic><topic>Humans</topic><topic>Ovarian Hyperstimulation Syndrome - complications</topic><topic>Ovarian Hyperstimulation Syndrome - drug therapy</topic><topic>Ovarian Hyperstimulation Syndrome - metabolism</topic><topic>Pituitary Neoplasms - complications</topic><topic>Pituitary Neoplasms - drug therapy</topic><topic>Pituitary Neoplasms - metabolism</topic><topic>spontaneous ovarian hyperstimulation syndrome</topic><toplevel>peer_reviewed</toplevel><toplevel>online_resources</toplevel><creatorcontrib>Knoepfelmacher, Mirta</creatorcontrib><creatorcontrib>Danilovic, Debora L.S.</creatorcontrib><creatorcontrib>Rosa Nasser, Rubia H.R.</creatorcontrib><creatorcontrib>Mendonça, Berenice B.</creatorcontrib><collection>ScienceDirect Open Access Titles</collection><collection>Elsevier:ScienceDirect:Open Access</collection><collection>Medline</collection><collection>MEDLINE</collection><collection>MEDLINE (Ovid)</collection><collection>MEDLINE</collection><collection>MEDLINE</collection><collection>PubMed</collection><collection>CrossRef</collection><collection>MEDLINE - Academic</collection><jtitle>Fertility and sterility</jtitle></facets><delivery><delcategory>Remote Search Resource</delcategory><fulltext>fulltext</fulltext></delivery><addata><au>Knoepfelmacher, Mirta</au><au>Danilovic, Debora L.S.</au><au>Rosa Nasser, Rubia H.R.</au><au>Mendonça, Berenice B.</au><format>journal</format><genre>article</genre><ristype>JOUR</ristype><atitle>Effectiveness of treating ovarian hyperstimulation syndrome with cabergoline in two patients with gonadotropin-producing pituitary adenomas</atitle><jtitle>Fertility and sterility</jtitle><addtitle>Fertil Steril</addtitle><date>2006-09-01</date><risdate>2006</risdate><volume>86</volume><issue>3</issue><spage>719.e15</spage><epage>719.e18</epage><pages>719.e15-719.e18</pages><issn>0015-0282</issn><eissn>1556-5653</eissn><abstract>To report the effect of cabergoline on ovarian hyperstimulation syndrome associated with gonadotropin-secreting pituitary adenomas.
Case report.
Outpatient practice.
Two women with menstrual irregularity, enlarged ovaries, high E2, and normal gonadotropin levels.
Cabergoline treatment and transsphenoidal surgery.
Estradiol levels, transvaginal ultrasonography, and pituitary magnetic resonance imaging. Transsphenoidal surgery showed pituitary adenoma staining for LH in both patients.
Cabergoline was effective in reducing E2 levels and decreasing ovarian size but ineffective in shrinking the pituitary adenomas.
This is the first description of the effectiveness of cabergoline as the primary treatment of spontaneous ovarian hyperstimulation syndrome in patients with gonadotropin-producing pituitary adenomas.</abstract><cop>United States</cop><pub>Elsevier Inc</pub><pmid>16952513</pmid><doi>10.1016/j.fertnstert.2006.01.055</doi><oa>free_for_read</oa></addata></record> |
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| source | MEDLINE; Elsevier ScienceDirect Journals; Elektronische Zeitschriftenbibliothek - Frei zugängliche E-Journals; Alma/SFX Local Collection |
| subjects | Adenoma Adult Antineoplastic Agents - therapeutic use cabergoline Ergolines - therapeutic use Female Gonadotropin-secreting pituitary adenoma Gonadotropins - metabolism Humans Ovarian Hyperstimulation Syndrome - complications Ovarian Hyperstimulation Syndrome - drug therapy Ovarian Hyperstimulation Syndrome - metabolism Pituitary Neoplasms - complications Pituitary Neoplasms - drug therapy Pituitary Neoplasms - metabolism spontaneous ovarian hyperstimulation syndrome |
| title | Effectiveness of treating ovarian hyperstimulation syndrome with cabergoline in two patients with gonadotropin-producing pituitary adenomas |
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