Significance of phrenic nerve electrophysiological abnormalities in Guillain-Barré syndrome

The authors investigated whether the amplitude and latency of diaphragm compound muscle action potential helped predict respiratory failure in Guillain-Barré syndrome. Both variables were significantly but weakly correlated with vital capacity (VC) and were similar in unventilated (n = 60) and venti...

Ausführliche Beschreibung

Gespeichert in:

Bibliographische Detailangaben
Veröffentlicht in:	Neurology 2005-11, Vol.65 (10), p.1646-1649
Hauptverfasser:	DURAND, M.-C, PRIGENT, H, SHARSHAR, T, SIVADON-TARDY, V, ORLIKOWSKI, D, CAUDIE, C, DEVAUX, C, CLAIR, B, GAILLARD, J.-L, LOFASO, F, RAPHAEL, J.-C
Format:	Artikel
Sprache:	eng
Schlagworte:	Action Potentials - physiology Adult Aged Biological and medical sciences Cranial nerves. Peripheral nerves. Autonomic nervous system Diaphragm - innervation Diaphragm - physiopathology Disease Progression Electrodiagnosis - methods Female Guillain-Barre Syndrome - complications Guillain-Barre Syndrome - physiopathology Humans Injuries of the nervous system and the skull. Diseases due to physical agents Male Medical sciences Middle Aged Muscle Contraction - physiology Muscle Weakness - diagnosis Muscle Weakness - etiology Muscle Weakness - physiopathology Neural Conduction - physiology Neurology Neurosurgery Phrenic Nerve - physiopathology Predictive Value of Tests Reaction Time - physiology Respiratory Center - physiopathology Respiratory Insufficiency - diagnosis Respiratory Insufficiency - etiology Respiratory Insufficiency - physiopathology Surgery (general aspects). Transplantations, organ and tissue grafts. Graft diseases Traumas. Diseases due to physical agents Vital Capacity - physiology
Online-Zugang:	Volltext
Tags:	Tag hinzufügen Keine Tags, Fügen Sie den ersten Tag hinzu!

Beschreibung
Zusammenfassung:	The authors investigated whether the amplitude and latency of diaphragm compound muscle action potential helped predict respiratory failure in Guillain-Barré syndrome. Both variables were significantly but weakly correlated with vital capacity (VC) and were similar in unventilated (n = 60) and ventilated (n = 10) patients. In ventilated patients, motor loss severity, progression, and VC reduction were significantly greater, and bulbar dysfunction was more common. Predicting respiratory failure must rely on clinical features and VC.
ISSN:	0028-3878 1526-632X
DOI:	10.1212/01.wnl.0000184589.62101.b9