Characterization of a novel B(A) allele with BBBA type at the ABO blood group
The ABO blood group is one of the main blood group systems, and it plays an important role in transfusion medicine and transplantation. To date, most of the many ABO subgroups with a weak expression of the A or B antigen on red blood cells have been elucidated to have specific molecular genetic back...
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Veröffentlicht in: | Journal of human genetics 2006-08, Vol.51 (8), p.732-736 |
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Hauptverfasser: | , , , , , |
Format: | Artikel |
Sprache: | eng |
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Zusammenfassung: | The ABO blood group is one of the main blood group systems, and it plays an important role in transfusion medicine and transplantation. To date, most of the many ABO subgroups with a weak expression of the A or B antigen on red blood cells have been elucidated to have specific molecular genetic background with respect to the
ABO
gene. The
ABO*B(A)
allele or
CisAB
allele is a type of dual
ABO
allele which can encode glycosyltransferases responsible for the conversion of H substance to both A and B antigen. We report here our characterization of a novel
B(A)
allele which differs from those reported previously. |
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ISSN: | 1434-5161 1435-232X |
DOI: | 10.1007/s10038-006-0013-5 |