Assessing recovery in middle cerebral artery stroke using functional MRI
Primary objective: To understand the temporal evolution of brain reorganization during recovery from stroke. Research design: A patient who suffered left middle cerebral artery stroke 9 months earlier was studied on three occasions, ∼1 month apart. Methods and procedures: Brain activation was studie...
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Veröffentlicht in: | Brain injury 2005-12, Vol.19 (13), p.1165-1176 |
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Sprache: | eng |
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Zusammenfassung: | Primary objective: To understand the temporal evolution of brain reorganization during recovery from stroke.
Research design: A patient who suffered left middle cerebral artery stroke 9 months earlier was studied on three occasions, ∼1 month apart.
Methods and procedures: Brain activation was studied using functional Magnetic Resonance Imaging (fMRI). During each session, the patient performed a finger-to-thumb opposition task, which involved one bimanual and two unimanual conditions. Each condition consisted of overt movement of fingers and imagery of the same task.
Results: With recovery, greater recruitment was observed of the affected primary motor cortex (M1) and a decrease in activation of the unaffected M1 and supplementary motor area. In addition, the widespread activation of brain areas seen during the initial session changed to a more focused pattern of activation as the patient recovered. Imagery tasks resulted in similar brain activity as overt execution pointing to imagery as a potential tool for rehabilitation. |
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ISSN: | 0269-9052 1362-301X |
DOI: | 10.1080/02699050500149858 |