A role for 3- O-sulfotransferase isoform-4 in assisting HSV-1 entry and spread

Many heparan sulfate (HS) 3- O-sulfotransferase (3- OST) isoforms generate cellular receptors for herpes simplex virus type-1 (HSV-1) glycoprotein D (gD). Interestingly, the ability of 3- OST-4 to mediate HSV-1 entry and cell-to-cell fusion has not been determined, although it is predominantly expre...

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Veröffentlicht in:	Biochemical and biophysical research communications 2005-12, Vol.338 (2), p.930-937
Hauptverfasser:	Tiwari, Vaibhav, O’Donnell, Christopher D., Oh, Myung-Jin, Valyi-Nagy, Tibor, Shukla, Deepak
Format:	Artikel
Sprache:	eng
Schlagworte:	3- O-Sulfotransferase-4 Animals CHO Cells Cricetinae Cricetulus Glycoprotein D Heparan sulfate Herpes simplex virus 1 Herpes simplex virus type-1 Herpesvirus 1, Human - physiology Membrane Fusion - physiology Protein Isoforms - metabolism Sulfotransferases - metabolism Virus Replication - physiology
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