Orthostatic hypotension in Parkinson's disease: association with cognitive decline?

Orthostatic hypotension in Parkinson's disease: association with cognitive decline?

Background Orthostatic hypotension is common in Lewy body disorders and may be related to disease progression and the spread of Lewy body pathology. We therefore hypothesize that PD patients with orthostatic hypotension (OH) have a different cognitive profile compared to PD patients without OH. Meth...

Ausführliche Beschreibung

Gespeichert in:
Bibliographische Detailangaben
Veröffentlicht in:International journal of geriatric psychiatry 2006-08, Vol.21 (8), p.778-783
Hauptverfasser: Allcock, Liesl M., Kenny, Rose Anne, Mosimann, Urs Peter, Tordoff, Sherley, Wesnes, Keith A., Hildreth, Anthony J., Burn, David J.
Format: Artikel
Sprache:eng
Schlagworte:
Aged
Attention
Biological and medical sciences
Blood Pressure
Cognition & reasoning
Cognition Disorders - etiology
cognitive deficits
Cross-Sectional Studies
Degenerative and inherited degenerative diseases of the nervous system. Leukodystrophies. Prion diseases
Female
Fundamental and applied biological sciences. Psychology
Geriatric psychiatry
Geriatrics
Humans
Hypotension, Orthostatic - complications
Hypotheses
Male
Medical sciences
Memory
Neurology
orthostatic hypotension
Parkinson Disease - complications
Parkinson's disease
Psychoanalysis
Psychology. Psychoanalysis. Psychiatry
Psychopathology. Psychiatry
Reaction Time
United Kingdom
Online-Zugang:Volltext
Tags: Tag hinzufügen
Keine Tags, Fügen Sie den ersten Tag hinzu!
Beschreibung
Zusammenfassung:Background Orthostatic hypotension is common in Lewy body disorders and may be related to disease progression and the spread of Lewy body pathology. We therefore hypothesize that PD patients with orthostatic hypotension (OH) have a different cognitive profile compared to PD patients without OH. Methods This cross‐sectional study included 175 PD patients. Blood pressure (BP) was measured with a validated digital blood pressure monitor and patients with a systolic BP drop of ≥20 mmHg or a systolic pressure of
ISSN:0885-6230
1099-1166
DOI:10.1002/gps.1562