The relationship of the round window membrane to the cochlear aqueduct shown in three-dimensional imaging

The round window membrane and cochlear aqueduct complex in the guinea pig are reconstructed with 3D-imaging, using orthogonal plane fluorescence optical sectioning (OPFOS). The 3D-images show that the periotic duct and the aqueduct are connected to a pouch-like extension of the round window. The fun...

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Veröffentlicht in:	Hearing research 2005-11, Vol.209 (1), p.19-23
Hauptverfasser:	Hofman, R., Segenhout, J.M., Albers, F.W.J., Wit, H.P.
Format:	Artikel
Sprache:	eng
Schlagworte:	Animals Biological and medical sciences Cochlear aqueduct Cochlear Aqueduct - anatomy & histology Drug toxicity and drugs side effects treatment Ear and associated structures. Auditory pathways and centers. Hearing. Vocal organ. Phonation. Sound production. Echolocation Female Flow resistance Fundamental and applied biological sciences. Psychology Guinea Pigs - anatomy & histology Imaging, Three-Dimensional - instrumentation Imaging, Three-Dimensional - methods Medical sciences OPFOS Perilymph Pharmacology. Drug treatments Round window membrane Round Window, Ear - anatomy & histology Toxicity: respiratory system, ent, stomatology Vertebrates: nervous system and sense organs
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Zusammenfassung:	The round window membrane and cochlear aqueduct complex in the guinea pig are reconstructed with 3D-imaging, using orthogonal plane fluorescence optical sectioning (OPFOS). The 3D-images show that the periotic duct and the aqueduct are connected to a pouch-like extension of the round window. The function of this may be regulation of aqueduct flow resistance under the influence of a pressure difference between inner ear fluid and middle ear.
ISSN:	0378-5955 1878-5891
DOI:	10.1016/j.heares.2005.06.004