Stepwise Differentiation of CD4 Memory T Cells Defined by Expression of CCR7 and CD27

To study the steps in the differentiation of human memory CD4 T cells, we characterized the functional and lineage relationships of three distinct memory CD4 subpopulations distinguished by their expression of the cysteine chemokine receptor CCR7 and the TNFR family member CD27. Using the combinatio...

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Veröffentlicht in:	Journal of Immunology 2005-11, Vol.175 (10), p.6489-6497
Hauptverfasser:	Fritsch, Ruth D, Shen, Xinglei, Sims, Gary P, Hathcock, Karen S, Hodes, Richard J, Lipsky, Peter E
Format:	Artikel
Sprache:	eng
Schlagworte:	Adult Apoptosis CD4-Positive T-Lymphocytes - cytology CD4-Positive T-Lymphocytes - immunology Cell Differentiation Cell Proliferation Cytokines - biosynthesis Female Humans Immunologic Memory In Vitro Techniques Male Receptors, CCR7 Receptors, Chemokine - metabolism T-Lymphocyte Subsets - cytology T-Lymphocyte Subsets - immunology Telomerase - biosynthesis Telomere - metabolism Tumor Necrosis Factor Receptor Superfamily, Member 7 - metabolism
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