NMR indicates that the small molecule RITA does not block p53-MDM2 binding in vitro
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| Veröffentlicht in: | Nature medicine 2005-11, Vol.11 (11), p.1135-1136 |
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| container_end_page | 1136 |
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| container_issue | 11 |
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| container_title | Nature medicine |
| container_volume | 11 |
| creator | Krajewski, Marcin Ozdowy, Przemyslaw D'Silva, Loyola Rothweiler, Ulli Holak, Tad A |
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| doi_str_mv | 10.1038/nm1105-1135 |
| format | Article |
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| identifier | ISSN: 1078-8956 |
| ispartof | Nature medicine, 2005-11, Vol.11 (11), p.1135-1136 |
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| subjects | Amino Acid Sequence Binding Sites Biomedical and Life Sciences Biomedicine Cancer Research Chromatography, Affinity correspondence Diffusion DNA-Binding Proteins - metabolism Gene Deletion Glutathione Transferase - metabolism Histidine - chemistry Humans Infectious Diseases Kinetics Metabolic Diseases Molecular Medicine Neoplasm Proteins - metabolism Neurosciences Nitrogen Isotopes - metabolism Nuclear Magnetic Resonance, Biomolecular Protein Binding Protein Conformation Protein Folding Protein Structure, Tertiary Proto-Oncogene Proteins c-mdm2 - chemistry Proto-Oncogene Proteins c-mdm2 - metabolism Protons Recombinant Fusion Proteins - metabolism Spectrometry, Fluorescence Titrimetry Tumor Suppressor Protein p53 - chemistry Tumor Suppressor Protein p53 - genetics Tumor Suppressor Protein p53 - isolation & purification Tumor Suppressor Protein p53 - metabolism |
| title | NMR indicates that the small molecule RITA does not block p53-MDM2 binding in vitro |
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