Genome-wide analysis of phenobarbital-inducible genes in Drosophila melanogaster

An oligoarray analysis was conducted to determine the differential expression of genes due to phenobarbital exposure in Drosophila melanogaster (w¹¹¹⁸ strain) third instar larvae. Seventeen genes were observed to be induced with increased expression by a statistical analysis of microarrays approach...

Ausführliche Beschreibung

Gespeichert in:

Bibliographische Detailangaben
Veröffentlicht in:	Insect molecular biology 2006-08, Vol.15 (4), p.455-464
Hauptverfasser:	Sun, W, Margam, V.M, Sun, L, Buczkowski, G, Bennett, G.W, Schemerhorn, B, Muir, W.M, Pittendrigh, B.R
Format:	Artikel
Sprache:	eng
Schlagworte:	Animals carbohydrate metabolism DDT (pesticide) differential gene expression DNA Primers Drosophila melanogaster Drosophila melanogaster - enzymology Drosophila melanogaster - genetics Enzymes - genetics Enzymes - metabolism gene expression regulation Gene Expression Regulation, Enzymologic - drug effects gene induction Genome - genetics GST insecticide resistance Larva - metabolism Microarray Analysis microarray technology oxido-reductase P450 phenobarbital Phenobarbital - pharmacology polymerase chain reaction quantitative real time polymerase chain reaction transcription (genetics)
Online-Zugang:	Volltext
Tags:	Tag hinzufügen Keine Tags, Fügen Sie den ersten Tag hinzu!

Beschreibung
Zusammenfassung:	An oligoarray analysis was conducted to determine the differential expression of genes due to phenobarbital exposure in Drosophila melanogaster (w¹¹¹⁸ strain) third instar larvae. Seventeen genes were observed to be induced with increased expression by a statistical analysis of microarrays approach with a q
ISSN:	0962-1075 1365-2583
DOI:	10.1111/j.1365-2583.2006.00662.x