DNA Integrity Assay: A Plasma-Based Screening Tool for the Detection of Prostate Cancer

Purpose: The aim of this study was to evaluate the utility of the DNA integrity assay (DIA) as a plasma-based screening tool for the detection of prostate cancer. Experimental Design: Blood samples were collected from patients with biopsy-proven prostate cancer prior to prostatectomy ( n = 123) and...

Ausführliche Beschreibung

Gespeichert in:

Bibliographische Detailangaben
Veröffentlicht in:	Clinical cancer research 2006-08, Vol.12 (15), p.4569-4574
Hauptverfasser:	HANLEY, Robert, RIEGER-CHRIST, Kimberly M, CANES, David, EMARA, Norah R, SHUBER, Anthony P, BOYNTON, Kevin A, LIBERTINO, John A, SUMMERHAYES, Ian C
Format:	Artikel
Sprache:	eng
Schlagworte:	Adult Antineoplastic agents Biological and medical sciences cell-free DNA DNA integrity assay (DIA) DNA, Neoplasm - blood DNA, Neoplasm - genetics Gynecology. Andrology. Obstetrics Humans Male Male genital diseases Medical sciences Middle Aged Nephrology. Urinary tract diseases Pharmacology. Drug treatments plasma, prostate cancer Predictive Value of Tests Prostatic Neoplasms - blood Prostatic Neoplasms - diagnosis Reverse Transcriptase Polymerase Chain Reaction - methods Sensitivity and Specificity Tumors Tumors of the urinary system Urinary tract. Prostate gland
Online-Zugang:	Volltext
Tags:	Tag hinzufügen Keine Tags, Fügen Sie den ersten Tag hinzu!

Beschreibung
Zusammenfassung:	Purpose: The aim of this study was to evaluate the utility of the DNA integrity assay (DIA) as a plasma-based screening tool for the detection of prostate cancer. Experimental Design: Blood samples were collected from patients with biopsy-proven prostate cancer prior to prostatectomy ( n = 123) and processed as two-spin plasma preparations. The three control groups included: males
ISSN:	1078-0432 1557-3265
DOI:	10.1158/1078-0432.CCR-06-0130