Inflammatory Reaction After Sirolimus-Eluting Stent Implant

Sirolimus-eluting stents (SES) are supposed to attenuate cell proliferation and reduce restenosis rate. Histologic finding from coronary artery after SES implant showed fibrosis and inflammatory infiltrate, revealing a chronic inflammatory reaction. Extension of coronary inflammatory reaction after...

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Veröffentlicht in:	The Annals of thoracic surgery 2005-11, Vol.80 (5), p.1903-1904
Hauptverfasser:	Gomes, Walter J., Giannotti-Filho, Oswaldo, Hossne, Nelson A., Catani, Roberto, Buffolo, Enio
Format:	Artikel
Sprache:	eng
Schlagworte:	Anti-Bacterial Agents - therapeutic use Biological and medical sciences Coronary Artery Bypass Coronary Restenosis - prevention & control Female Humans Inflammation - etiology Inflammation - physiopathology Male Medical sciences Middle Aged Sirolimus - therapeutic use Stents - adverse effects Surgery (general aspects). Transplantations, organ and tissue grafts. Graft diseases Surgery of the respiratory system
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Beschreibung
Zusammenfassung:	Sirolimus-eluting stents (SES) are supposed to attenuate cell proliferation and reduce restenosis rate. Histologic finding from coronary artery after SES implant showed fibrosis and inflammatory infiltrate, revealing a chronic inflammatory reaction. Extension of coronary inflammatory reaction after stenting needs clarification. The long-term consequences are unknown.
ISSN:	0003-4975 1552-6259
DOI:	10.1016/j.athoracsur.2004.05.079