Serum aluminium and cobalt levels after ceramic-on-ceramic and metal-on-metal total hip replacement

In a randomised study, 28 patients with a mean age of 62.2 years (32 to 81) with osteoarthritis or avascular necrosis of the hip received either a ceramic-on-ceramic or a metal-on-metal total hip replacement. Apart from the liners the acetabular and femoral components were made of Ti-Al-Nb alloy. Th...

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Veröffentlicht in:Journal of bone and joint surgery. British volume 2006-08, Vol.88 (8), p.1003-1005
Hauptverfasser: GRÜBL, A, WEISSINGER, M, BRODNER, W, GLEISS, A, GIUREA, A, GRUBER, M, POLL, G, MEISINGER, V, GOTTSAUNER-WOLF, F, KOTZ, R
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Sprache:eng
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Zusammenfassung:In a randomised study, 28 patients with a mean age of 62.2 years (32 to 81) with osteoarthritis or avascular necrosis of the hip received either a ceramic-on-ceramic or a metal-on-metal total hip replacement. Apart from the liners the acetabular and femoral components were made of Ti-Al-Nb alloy. The serum aluminium and cobalt levels were measured before, and at one year after surgery. The 15 patients in the ceramic-on-ceramic group had a median pre-operative aluminium level of 1.3 microg/l (0.25 to 8.4) and a cobalt level below the detection limit. At one year the aluminium level was 1.1 microg/l (0.25 to 2.3) and the cobalt level was 0.4 microg/l (0.15 to 0.7). The 13 patients in the metal-on-metal group had a median pre-operative aluminium level of 1.9 microg/l (0.25 to 4.4) and a cobalt level below the detection limit. At one year the median aluminium level was 0.9 microg/l (0.25 to 3.9) whereas the cobalt level was 1.4 microg/l (0.5 to 10.5). This increase in the cobalt level at one year was significant (p < 0.001). Our findings indicate that ceramic-on-ceramic bearings do not cause elevated levels of serum aluminium in the first post-operative year.
ISSN:0301-620X
2049-4394
2044-5377
2049-4408
DOI:10.1302/0301-620X.88B8.17870