Complete remission in a pancytopenic HIV negative, HHV-8 positive patient with multicentric Castleman's disease induced with anti-CD20
A 75-year-old woman was diagnosed of MCD plasma cell (PC) variant with B symptoms. Diffuse lymph-node enlargement, splenomegaly and pancytopenia were detected. Induction with Rituximab was made because pancytopenia was present. Actually patient is free of disease. This is the first complete response...
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Veröffentlicht in: | Clinical & translational oncology 2006-07, Vol.8 (7), p.540-541 |
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creator | Cervera Grau, J M Galiana Esquerdo, G Llorca Ferrándiz, C Briceño García, H Díaz Castellano, M Férriz Moreno, P |
description | A 75-year-old woman was diagnosed of MCD plasma cell (PC) variant with B symptoms. Diffuse lymph-node enlargement, splenomegaly and pancytopenia were detected. Induction with Rituximab was made because pancytopenia was present. Actually patient is free of disease. This is the first complete response of MCD published, VIH negative, induced with anti CD20. |
doi_str_mv | 10.1007/s12094-006-0056-2 |
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Diffuse lymph-node enlargement, splenomegaly and pancytopenia were detected. Induction with Rituximab was made because pancytopenia was present. Actually patient is free of disease. This is the first complete response of MCD published, VIH negative, induced with anti CD20.</description><identifier>ISSN: 1699-048X</identifier><identifier>EISSN: 1699-3055</identifier><identifier>DOI: 10.1007/s12094-006-0056-2</identifier><identifier>PMID: 16870545</identifier><language>eng</language><publisher>Italy</publisher><subject>Aged ; Antibodies, Monoclonal - therapeutic use ; Antibodies, Monoclonal, Murine-Derived ; Antigens, CD20 ; Antineoplastic Combined Chemotherapy Protocols - therapeutic use ; Castleman Disease - complications ; Castleman Disease - drug therapy ; Castleman Disease - immunology ; Female ; Herpesviridae Infections - complications ; Herpesvirus 8, Human ; HIV Seronegativity ; Humans ; Pancytopenia - complications ; Remission Induction ; Rituximab</subject><ispartof>Clinical & translational oncology, 2006-07, Vol.8 (7), p.540-541</ispartof><lds50>peer_reviewed</lds50><woscitedreferencessubscribed>false</woscitedreferencessubscribed><citedby>FETCH-LOGICAL-c214t-c362da9c867fd7f109b65a74206b5015a7566e17636ff56341ae27ab258813e93</citedby><cites>FETCH-LOGICAL-c214t-c362da9c867fd7f109b65a74206b5015a7566e17636ff56341ae27ab258813e93</cites></display><links><openurl>$$Topenurl_article</openurl><openurlfulltext>$$Topenurlfull_article</openurlfulltext><thumbnail>$$Tsyndetics_thumb_exl</thumbnail><link.rule.ids>314,776,780,27901,27902</link.rule.ids><backlink>$$Uhttps://www.ncbi.nlm.nih.gov/pubmed/16870545$$D View this record in MEDLINE/PubMed$$Hfree_for_read</backlink></links><search><creatorcontrib>Cervera Grau, J M</creatorcontrib><creatorcontrib>Galiana Esquerdo, G</creatorcontrib><creatorcontrib>Llorca Ferrándiz, C</creatorcontrib><creatorcontrib>Briceño García, H</creatorcontrib><creatorcontrib>Díaz Castellano, M</creatorcontrib><creatorcontrib>Férriz Moreno, P</creatorcontrib><title>Complete remission in a pancytopenic HIV negative, HHV-8 positive patient with multicentric Castleman's disease induced with anti-CD20</title><title>Clinical & translational oncology</title><addtitle>Clin Transl Oncol</addtitle><description>A 75-year-old woman was diagnosed of MCD plasma cell (PC) variant with B symptoms. Diffuse lymph-node enlargement, splenomegaly and pancytopenia were detected. Induction with Rituximab was made because pancytopenia was present. Actually patient is free of disease. This is the first complete response of MCD published, VIH negative, induced with anti CD20.</description><subject>Aged</subject><subject>Antibodies, Monoclonal - therapeutic use</subject><subject>Antibodies, Monoclonal, Murine-Derived</subject><subject>Antigens, CD20</subject><subject>Antineoplastic Combined Chemotherapy Protocols - therapeutic use</subject><subject>Castleman Disease - complications</subject><subject>Castleman Disease - drug therapy</subject><subject>Castleman Disease - immunology</subject><subject>Female</subject><subject>Herpesviridae Infections - complications</subject><subject>Herpesvirus 8, Human</subject><subject>HIV Seronegativity</subject><subject>Humans</subject><subject>Pancytopenia - complications</subject><subject>Remission Induction</subject><subject>Rituximab</subject><issn>1699-048X</issn><issn>1699-3055</issn><fulltext>true</fulltext><rsrctype>article</rsrctype><creationdate>2006</creationdate><recordtype>article</recordtype><sourceid>EIF</sourceid><recordid>eNpFkMtKxDAUhoMo3h_AjWSlG6tJ2py2S6mXGRDc6OAuZNJTjbRpbVJlXsDnNsMMuAg5B77_h_MRcsbZNWcsv_FcsDJLGIP4JCRihxxyKMskZVLubmeWFW8H5Mj7z8hI4HyfHHAociYzeUh-q74bWgxIR-ys97Z31Dqq6aCdWYV-QGcNnc0X1OG7DvYbr-hstkgKOvTervdIBosu0B8bPmg3tcGauI4xVmkfWuy0u_S0th61x1heTwbrDa1dsEl1J9gJ2Wt06_F0-x-T14f7l2qWPD0_zqvbp8QInoXEpCBqXZoC8qbOG87KJUidZ4LBUjIeRwmAPIcUmkZCmnGNItdLIYuCp1imx-Ri0zuM_deEPqh4tMG21Q77ySuIzQBcRJBvQDP23o_YqGG0nR5XijO1lq828lWUr9by1Tpzvi2flh3W_4mt7fQPWdN_8g</recordid><startdate>200607</startdate><enddate>200607</enddate><creator>Cervera Grau, J M</creator><creator>Galiana Esquerdo, G</creator><creator>Llorca Ferrándiz, C</creator><creator>Briceño García, H</creator><creator>Díaz Castellano, M</creator><creator>Férriz Moreno, P</creator><scope>CGR</scope><scope>CUY</scope><scope>CVF</scope><scope>ECM</scope><scope>EIF</scope><scope>NPM</scope><scope>AAYXX</scope><scope>CITATION</scope><scope>7X8</scope></search><sort><creationdate>200607</creationdate><title>Complete remission in a pancytopenic HIV negative, HHV-8 positive patient with multicentric Castleman's disease induced with anti-CD20</title><author>Cervera Grau, J M ; Galiana Esquerdo, G ; Llorca Ferrándiz, C ; Briceño García, H ; Díaz Castellano, M ; Férriz Moreno, P</author></sort><facets><frbrtype>5</frbrtype><frbrgroupid>cdi_FETCH-LOGICAL-c214t-c362da9c867fd7f109b65a74206b5015a7566e17636ff56341ae27ab258813e93</frbrgroupid><rsrctype>articles</rsrctype><prefilter>articles</prefilter><language>eng</language><creationdate>2006</creationdate><topic>Aged</topic><topic>Antibodies, Monoclonal - therapeutic use</topic><topic>Antibodies, Monoclonal, Murine-Derived</topic><topic>Antigens, CD20</topic><topic>Antineoplastic Combined Chemotherapy Protocols - therapeutic use</topic><topic>Castleman Disease - complications</topic><topic>Castleman Disease - drug therapy</topic><topic>Castleman Disease - immunology</topic><topic>Female</topic><topic>Herpesviridae Infections - complications</topic><topic>Herpesvirus 8, Human</topic><topic>HIV Seronegativity</topic><topic>Humans</topic><topic>Pancytopenia - complications</topic><topic>Remission Induction</topic><topic>Rituximab</topic><toplevel>peer_reviewed</toplevel><toplevel>online_resources</toplevel><creatorcontrib>Cervera Grau, J M</creatorcontrib><creatorcontrib>Galiana Esquerdo, G</creatorcontrib><creatorcontrib>Llorca Ferrándiz, C</creatorcontrib><creatorcontrib>Briceño García, H</creatorcontrib><creatorcontrib>Díaz Castellano, M</creatorcontrib><creatorcontrib>Férriz Moreno, P</creatorcontrib><collection>Medline</collection><collection>MEDLINE</collection><collection>MEDLINE (Ovid)</collection><collection>MEDLINE</collection><collection>MEDLINE</collection><collection>PubMed</collection><collection>CrossRef</collection><collection>MEDLINE - Academic</collection><jtitle>Clinical & translational oncology</jtitle></facets><delivery><delcategory>Remote Search Resource</delcategory><fulltext>fulltext</fulltext></delivery><addata><au>Cervera Grau, J M</au><au>Galiana Esquerdo, G</au><au>Llorca Ferrándiz, C</au><au>Briceño García, H</au><au>Díaz Castellano, M</au><au>Férriz Moreno, P</au><format>journal</format><genre>article</genre><ristype>JOUR</ristype><atitle>Complete remission in a pancytopenic HIV negative, HHV-8 positive patient with multicentric Castleman's disease induced with anti-CD20</atitle><jtitle>Clinical & translational oncology</jtitle><addtitle>Clin Transl Oncol</addtitle><date>2006-07</date><risdate>2006</risdate><volume>8</volume><issue>7</issue><spage>540</spage><epage>541</epage><pages>540-541</pages><issn>1699-048X</issn><eissn>1699-3055</eissn><abstract>A 75-year-old woman was diagnosed of MCD plasma cell (PC) variant with B symptoms. Diffuse lymph-node enlargement, splenomegaly and pancytopenia were detected. Induction with Rituximab was made because pancytopenia was present. Actually patient is free of disease. This is the first complete response of MCD published, VIH negative, induced with anti CD20.</abstract><cop>Italy</cop><pmid>16870545</pmid><doi>10.1007/s12094-006-0056-2</doi><tpages>2</tpages></addata></record> |
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subjects | Aged Antibodies, Monoclonal - therapeutic use Antibodies, Monoclonal, Murine-Derived Antigens, CD20 Antineoplastic Combined Chemotherapy Protocols - therapeutic use Castleman Disease - complications Castleman Disease - drug therapy Castleman Disease - immunology Female Herpesviridae Infections - complications Herpesvirus 8, Human HIV Seronegativity Humans Pancytopenia - complications Remission Induction Rituximab |
title | Complete remission in a pancytopenic HIV negative, HHV-8 positive patient with multicentric Castleman's disease induced with anti-CD20 |
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