Complete remission in a pancytopenic HIV negative, HHV-8 positive patient with multicentric Castleman's disease induced with anti-CD20

A 75-year-old woman was diagnosed of MCD plasma cell (PC) variant with B symptoms. Diffuse lymph-node enlargement, splenomegaly and pancytopenia were detected. Induction with Rituximab was made because pancytopenia was present. Actually patient is free of disease. This is the first complete response...

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Veröffentlicht in:Clinical & translational oncology 2006-07, Vol.8 (7), p.540-541
Hauptverfasser: Cervera Grau, J M, Galiana Esquerdo, G, Llorca Ferrándiz, C, Briceño García, H, Díaz Castellano, M, Férriz Moreno, P
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container_end_page 541
container_issue 7
container_start_page 540
container_title Clinical & translational oncology
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creator Cervera Grau, J M
Galiana Esquerdo, G
Llorca Ferrándiz, C
Briceño García, H
Díaz Castellano, M
Férriz Moreno, P
description A 75-year-old woman was diagnosed of MCD plasma cell (PC) variant with B symptoms. Diffuse lymph-node enlargement, splenomegaly and pancytopenia were detected. Induction with Rituximab was made because pancytopenia was present. Actually patient is free of disease. This is the first complete response of MCD published, VIH negative, induced with anti CD20.
doi_str_mv 10.1007/s12094-006-0056-2
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subjects Aged
Antibodies, Monoclonal - therapeutic use
Antibodies, Monoclonal, Murine-Derived
Antigens, CD20
Antineoplastic Combined Chemotherapy Protocols - therapeutic use
Castleman Disease - complications
Castleman Disease - drug therapy
Castleman Disease - immunology
Female
Herpesviridae Infections - complications
Herpesvirus 8, Human
HIV Seronegativity
Humans
Pancytopenia - complications
Remission Induction
Rituximab
title Complete remission in a pancytopenic HIV negative, HHV-8 positive patient with multicentric Castleman's disease induced with anti-CD20
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