Alternative Splicing— When Two’s a Crowd

Various mechanisms have been proposed to explain mutually exclusive splicing of pairs of exons. A paper in this issue of Cell ( Graveley, 2005) provides a fascinating insight into the perplexing question of how only one exon at a time is chosen from an array of 48 exons in the Drosophila Dscam gene.

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Veröffentlicht in:Cell 2005-10, Vol.123 (1), p.1-3
1. Verfasser: Smith, Christopher W.J.
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description Various mechanisms have been proposed to explain mutually exclusive splicing of pairs of exons. A paper in this issue of Cell ( Graveley, 2005) provides a fascinating insight into the perplexing question of how only one exon at a time is chosen from an array of 48 exons in the Drosophila Dscam gene.
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subjects Alternative Splicing - genetics
Animals
Cell Adhesion Molecules
Drosophila
Drosophila melanogaster - genetics
Drosophila Proteins - biosynthesis
Drosophila Proteins - genetics
Exons - genetics
Gene Expression Regulation - genetics
Humans
RNA Splice Sites - genetics
RNA, Messenger - genetics
RNA, Messenger - metabolism
Spliceosomes - genetics
title Alternative Splicing— When Two’s a Crowd
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