Accelerating chemical replication steps of RNA involving activated ribonucleotides and downstream-binding elements

Template-directed single nucleotide extension of an RNA primer with oxyazabenzotriazolides of ribonucleotides is shown to be fast and sequence-selective; downstream-binding RNA strands contribute to the acceleration of the reaction.

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Veröffentlicht in:Chemical communications (Cambridge, England) England), 2005-10 (39), p.4922-4924
Hauptverfasser: Vogel, Stephanie R, Deck, Christopher, Richert, Clemens
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container_title Chemical communications (Cambridge, England)
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creator Vogel, Stephanie R
Deck, Christopher
Richert, Clemens
description Template-directed single nucleotide extension of an RNA primer with oxyazabenzotriazolides of ribonucleotides is shown to be fast and sequence-selective; downstream-binding RNA strands contribute to the acceleration of the reaction.
doi_str_mv 10.1039/b510775j
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source Royal Society of Chemistry Journals Archive (1841-2007); MEDLINE; Royal Society Of Chemistry Journals 2008-; Alma/SFX Local Collection
subjects Base Sequence
Hydrogen-Ion Concentration
Kinetics
Molecular Sequence Data
Ribonucleotides - chemistry
RNA - chemical synthesis
RNA - chemistry
Temperature
title Accelerating chemical replication steps of RNA involving activated ribonucleotides and downstream-binding elements
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