Genotypic analysis of Mycobacterium leprae isolates from Japan and other Asian countries reveals a global transmission pattern of leprosy

Abstract The genotype of single-nucleotide polymorphism type 3, CTC, at positions 14676, 164275, and 2935685, along with four copies of 6bp repeats in the rpoT gene, was predominant for isolates originating in the Japanese mainland. Type 1, CGA, type 2, CTA, and type 3 were detected from Korea, Indo...

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Veröffentlicht in:	FEMS microbiology letters 2006-08, Vol.261 (1), p.150-154
Hauptverfasser:	Matsuoka, Masanori, Roa, Rocio Ivette Lopez, Budiawan, Teky, Kyaw, Kyaw, Chae, Gue-Tae
Format:	Artikel
Sprache:	eng
Schlagworte:	Adolescent Adult Animals Asia - epidemiology Bacterial Proteins - genetics Bacteriology Biological and medical sciences Brazil Female Fundamental and applied biological sciences. Psychology Gene polymorphism Genes. Genome Genetics Genotype genotyping Humans Japan - epidemiology Leprosy Leprosy - transmission Male Mice Mice, Nude Microbiology Middle Aged Molecular and cellular biology Molecular genetics Mycobacterium leprae Mycobacterium leprae - genetics Mycobacterium leprae - isolation & purification Nucleotides Polymorphism Polymorphism, Single Nucleotide Repetitive Sequences, Nucleic Acid RpoT gene Sigma Factor - genetics Single-nucleotide polymorphism SNPs VNTRs
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